在抗 CRISPR 丛林中，只有弱者才能生存？

In the Anti-CRISPR Jungle, Only the Weak Thrive?

机构信息

Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada.

Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada; Farncombe Family Digestive Health Research Institute, Department of Medicine, McMaster University, Hamilton, ON L8S 4K1, Canada.

出版信息

Cell Host Microbe. 2020 Feb 12;27(2):157-159. doi: 10.1016/j.chom.2020.01.019.

DOI:10.1016/j.chom.2020.01.019

PMID:32053781

Abstract

If, as we all know, only the strong survive, why do bacterial viruses (phages) encode weak suppressors of a bacterial immune system? In this issue of Cell Host & Microbe, Chevallereau et al. (2019) expertly demonstrate how, in the context of competition with other phages, weakness can be a strength.

摘要

如果像我们大家都知道的那样，只有强者才能生存，那么为什么细菌病毒（噬菌体）会编码弱化的细菌免疫系统抑制剂呢？在本期的《细胞宿主与微生物》中，Chevallereau 等人（2019）精彩地展示了在与其他噬菌体竞争的情况下，弱点如何成为一种优势。