Tunthanathip Thara, Kanjanapradit Kanet
Department of Surgery, Division of Neurosurgery, Prince of Songkla University, Songkhla, Thailand.
Department of Pathology, Faculty of Medicine, Songklanagarind Hospital, Prince of Songkla University, Songkhla, Thailand.
Ann Indian Acad Neurol. 2020 Jan-Feb;23(1):103-106. doi: 10.4103/aian.AIAN_219_18.
Although microvascular proliferation can be observed in glioblastoma, obvious vascularity coupled with coexisting cerebral arteriovenous malformation (AVM) is extremely rare. This report is of a rare case of glioblastoma, coexisting with a cerebral AVM. A 20-year-old male presented with progressive right hemiparesis within 1 month. Cranial magnetic resonance imaging revealed a large bleeding tumor with surrounding dilated vessels. Cerebral angiography demonstrated a left frontal AVM with a 1.2 cm nidus. The patient underwent preoperative embolization and radical resection. The coincidence of glioma and AVM was a rare association. However, the concept of hypervascular glioblastoma has been used in different states from different literature reviews; therefore, the role of proangiogenic factors should be addressed.
尽管在胶质母细胞瘤中可观察到微血管增殖，但明显的血管形成并伴有并存的脑动静脉畸形（AVM）极为罕见。本报告介绍了一例罕见的胶质母细胞瘤病例，并存有脑AVM。一名20岁男性在1个月内出现进行性右侧偏瘫。头颅磁共振成像显示一个伴有周围血管扩张的大出血性肿瘤。脑血管造影显示左侧额叶有一个1.2厘米大小的动静脉畸形病灶。该患者接受了术前栓塞和根治性切除术。胶质瘤与AVM的并存是一种罕见的关联。然而，不同的文献综述对高血管性胶质母细胞瘤这一概念的使用情况各异；因此，应探讨促血管生成因子的作用。
