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Male Fertility as a Proxy for Health.男性生育能力作为健康的一个指标。
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Clinical correlation among male infertility and overall male health: A systematic review of the literature.男性不育与整体男性健康的临床相关性:文献系统综述。
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Chronic exposures and male fertility: the impacts of environment, diet, and drug use on spermatogenesis.慢性暴露与男性生育能力:环境、饮食及药物使用对精子发生的影响。
Andrology. 2016 Jul;4(4):648-61. doi: 10.1111/andr.12198. Epub 2016 May 27.

引用本文的文献

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From Inflammation to Infertility: How Oxidative Stress and Infections Disrupt Male Reproductive Health.从炎症到不育:氧化应激和感染如何破坏男性生殖健康。
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Phosphodiesterase Type 5 Inhibitors in Male Reproduction: Molecular Mechanisms and Clinical Implications for Fertility Management.5型磷酸二酯酶抑制剂在男性生殖中的作用:分子机制及对生育管理的临床意义
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本文引用的文献

1
Describing patterns of familial cancer risk in subfertile men using population pedigree data.利用人群系谱数据描述生育能力低下男性家族性癌症风险的模式。
Hum Reprod. 2024 Apr 3;39(4):822-833. doi: 10.1093/humrep/dead270.
2
A DNA Methylation Perspective on Infertility.从 DNA 甲基化角度看不孕不育。
Genes (Basel). 2023 Nov 27;14(12):2132. doi: 10.3390/genes14122132.
3
"No One Asked Me If I'm Alright": A Mixed-Methods Study Exploring Information/Support Needs and Challenges Engaging Men Diagnosed With Male-Factor Infertility.“没人问我是否还好”:一项混合方法研究,探讨了男性因素不孕诊断后男性的信息/支持需求和参与挑战。
Am J Mens Health. 2023 Nov-Dec;17(6):15579883231209210. doi: 10.1177/15579883231209210.
4
Out-of-Pocket Costs for Men Undergoing Infertility Care and Associated Financial Strain.接受不孕不育治疗男性的自付费用及相关经济压力
Urol Pract. 2016 Jul;3(4):256-261. doi: 10.1016/j.urpr.2015.07.010. Epub 2016 Apr 21.
5
Phthalate-induced testosterone/androgen receptor pathway disorder on spermatogenesis and antagonism of lycopene.邻苯二甲酸酯诱导的睾丸生殖细胞中睾酮/雄激素受体信号通路紊乱及其对番茄红素的拮抗作用。
J Hazard Mater. 2022 Oct 5;439:129689. doi: 10.1016/j.jhazmat.2022.129689. Epub 2022 Jul 27.
6
Risk of cardiovascular disease in women and men with subfertility: the Trøndelag Health Study.生育能力低下的男性和女性患心血管疾病的风险:特隆赫姆健康研究。
Fertil Steril. 2022 Sep;118(3):537-547. doi: 10.1016/j.fertnstert.2022.05.038. Epub 2022 Jul 13.
7
Genomic instability and the link to infertility: A focus on microsatellites and genomic instability syndromes.基因组不稳定性与不孕的关联:关注微卫星和基因组不稳定性综合征。
Eur J Obstet Gynecol Reprod Biol. 2022 Jul;274:229-237. doi: 10.1016/j.ejogrb.2022.06.001. Epub 2022 Jun 3.
8
Metabolic Syndrome and Male Fertility: Beyond Heart Consequences of a Complex Cardiometabolic Endocrinopathy.代谢综合征与男性生育力:超越复杂心脏代谢内分泌病的心脏后果。
Int J Mol Sci. 2022 May 14;23(10):5497. doi: 10.3390/ijms23105497.
9
Male Infertility Increases the Risk of Cardiovascular Diseases: A Nationwide Population-Based Cohort Study in Taiwan.男性不育增加心血管疾病风险:台湾一项基于全国人口的队列研究
World J Mens Health. 2022 Jul;40(3):490-500. doi: 10.5534/wjmh.210098. Epub 2022 Jan 1.
10
Cancer testis antigens and genomic instability: More than immunology.癌症睾丸抗原与基因组不稳定性:超越免疫学。
DNA Repair (Amst). 2021 Dec;108:103214. doi: 10.1016/j.dnarep.2021.103214. Epub 2021 Aug 17.

男性生育能力作为健康的一个指标。

Male Fertility as a Proxy for Health.

作者信息

Zhao Calvin C, Scott Michael, Eisenberg Michael L

机构信息

Department of Urology, Stanford University School of Medicine, Stanford, CA 94305, USA.

出版信息

J Clin Med. 2024 Sep 19;13(18):5559. doi: 10.3390/jcm13185559.

DOI:10.3390/jcm13185559
PMID:39337044
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11432267/
Abstract

Male fertility is affected by a wide range of medical conditions that directly and indirectly affect spermatogenesis. As such, it can be useful as both an indicator of current health and a predictive factor for future health outcomes. Herein, we discuss the current literature regarding the association between male fertility and systemic health conditions and exposures. We review the connection between male fertility and genetics, medications, diet, and environmental pollutants, as well as its effects on future oncologic, cardiovascular, and autoimmune conditions. Understanding this interplay will allow more health care providers to engage in health counseling that will not only improve men's reproductive outcomes but also their overall health.

摘要

男性生育能力受到多种直接或间接影响精子发生的医学状况的影响。因此,它既可以作为当前健康状况的指标,也可以作为未来健康结果的预测因素。在此,我们讨论当前关于男性生育能力与全身健康状况及暴露因素之间关联的文献。我们回顾男性生育能力与遗传学、药物、饮食和环境污染物之间的联系,以及其对未来肿瘤、心血管和自身免疫性疾病的影响。了解这种相互作用将使更多医疗保健提供者能够进行健康咨询,这不仅会改善男性的生殖结果,还会提升他们的整体健康水平。