Department of Neurosurgery, Inje University Haeundae Paik Hospital, 875, Haeun-daero, Haeundae-gu, Busan, Republic of Korea.
Department of Neurology, Inje University Haeundae Paik Hospital, Busan, South Korea.
Neuroradiology. 2020 Jun;62(6):723-731. doi: 10.1007/s00234-020-02376-1. Epub 2020 Feb 13.
Acute vertebrobasilar occlusion (VBO) has a grave clinical course; however, thrombectomy in VBO patients has rarely been reported. We retrospectively evaluated the clinical and radiological outcomes of thrombectomy in VBO patients.
From March 2010 to December 2017, 38 patients with 40 acute VBOs underwent thrombectomy at our hospital. Thrombectomy was performed using catheter aspiration (n = 11, 26.8%) or a stent retriever (n = 29, 70.7%).
Good clinical outcomes (3-month modified Rankin scale (mRS) of 2 or lower) were achieved in 9 cases (22.5%), and successful recanalization (thrombolysis in cerebral infarction (TICI) grade of 2b or 3) was achieved in 35 cases (87.5%). Good clinical outcomes were significantly related to aetiologies other than atherosclerosis (p = 0.020) and lower National Institutes of Health Stroke Scale (NIHSS) scores on admission (p = 0.025). The clinical and radiological outcomes did not differ significantly between catheter aspiration and stent retriever thrombectomy (p = 1.000 and p = 0.603, respectively); however, stent retriever thrombectomy had a shorter procedure time than catheter aspiration (59.7 ± 31.2 vs. 84.5 ± 35.1 min, p = 0.037).
In our series, good clinical outcomes were associated with a lower NIHSS score on admission and stroke aetiologies other than atherosclerosis. The two thrombectomy modalities showed similar clinical and radiological outcomes. However, stent retrievers seemed to allow more rapid recanalization than catheter aspiration in VBO.
急性椎基底动脉闭塞(VBO)具有严重的临床病程;然而,VBO 患者的血栓切除术很少有报道。我们回顾性评估了 VBO 患者血栓切除术的临床和影像学结果。
2010 年 3 月至 2017 年 12 月,我院 38 例 40 例急性 VBO 患者行血栓切除术。采用导管抽吸(n=11,26.8%)或支架取栓器(n=29,70.7%)进行血栓切除术。
9 例(22.5%)获得良好的临床转归(3 个月改良 Rankin 量表(mRS)为 2 或更低),35 例(87.5%)实现了成功再通(血栓溶解脑梗死(TICI)分级 2b 或 3)。良好的临床转归与动脉粥样硬化以外的病因(p=0.020)和入院时较低的国立卫生研究院卒中量表(NIHSS)评分(p=0.025)显著相关。导管抽吸和支架取栓器血栓切除术的临床和影像学结果无显著差异(p=1.000 和 p=0.603);然而,支架取栓器血栓切除术的手术时间短于导管抽吸(59.7±31.2 分钟比 84.5±35.1 分钟,p=0.037)。
在我们的系列研究中,良好的临床转归与入院时较低的 NIHSS 评分和动脉粥样硬化以外的中风病因相关。两种血栓切除术方法的临床和影像学结果相似。然而,支架取栓器似乎比导管抽吸更能迅速使 VBO 再通。