Stress Research Institute, Stockholm University, SE-106 91 Stockholm, Sweden.
Department of Public Health, Copenhagen University, Denmark.
J Affect Disord. 2020 Apr 1;266:215-222. doi: 10.1016/j.jad.2020.01.078. Epub 2020 Jan 20.
Previous research suggests that job insecurity is associated with poor mental health, but research examining how different aspects of job insecurity relate to clinical measures of poor mental health are lacking. We aimed to investigate the association between cognitive and affective job insecurity and incident purchases of psychotropic drugs.
We included 14,586 employees participating in the Swedish Longitudinal Occupational Survey of Health (SLOSH), who answered questions on cognitive and/or affective job insecurity in 2010, 2012 or 2014. Respondents were followed in the Swedish Prescribed Drug Register (2.5 years on average). We investigated the association between job insecurity and incident psychotropic drugs with marginal structural Cox models.
Affective job insecurity was associated with an increased risk of purchasing any psychotropic drugs (Hazard Ratio (HR) 1.40 (95% Confidence Interval (CI) 1.04-1.89)) while cognitive job insecurity was not (HR 1.15 (95% CI 0.92-1.43)). Cognitive and affective job insecurity were both associated with antidepressants, affective job insecurity with anxiolytics, but no association was found with sedatives. Women and younger workers seemed to have higher risk compared to men and older workers, but differences were not statistically significant.
Although job insecurity and psychotropic drugs were assessed through independent sources and several covariates were considered, unmeasured confounding cannot be ruled out.
The findings support that affective job insecurity is a risk factor for psychotropic drug treatment, that it may be relevant to distinguish between different types of job insecurity, and to consider sex and age as moderating factors.
先前的研究表明,工作不安全感与心理健康状况不佳有关,但缺乏研究来检验工作不安全感的不同方面与心理健康不良的临床测量指标之间的关系。我们旨在调查认知和情感工作不安全感与精神药物购买事件之间的关联。
我们纳入了 14586 名参与瑞典纵向职业健康调查(SLOSH)的员工,他们在 2010 年、2012 年或 2014 年回答了关于认知和/或情感工作不安全感的问题。被随访者在瑞典处方药物登记处(平均 2.5 年)。我们使用边缘结构 Cox 模型调查了工作不安全感与精神药物购买事件之间的关联。
情感工作不安全感与购买任何精神药物的风险增加相关(危险比 (HR) 1.40(95%置信区间 (CI) 1.04-1.89)),而认知工作不安全感则没有(HR 1.15(95% CI 0.92-1.43))。认知和情感工作不安全感都与抗抑郁药有关,情感工作不安全感与抗焦虑药有关,但与镇静剂无关。与男性和老年工人相比,女性和年轻工人的风险似乎更高,但差异无统计学意义。
尽管工作不安全感和精神药物是通过独立的来源评估的,并且考虑了几个协变量,但不能排除未测量的混杂因素。
研究结果支持情感工作不安全感是精神药物治疗的危险因素,可能需要区分不同类型的工作不安全感,并考虑性别和年龄作为调节因素。