Suppr超能文献

认知和情感工作不安全感与购买精神药物事件之间的关联:一项对瑞典员工的前瞻性队列研究。

Associations between cognitive and affective job insecurity and incident purchase of psychotropic drugs: A prospective cohort study of Swedish employees.

机构信息

Stress Research Institute, Stockholm University, SE-106 91 Stockholm, Sweden.

Department of Public Health, Copenhagen University, Denmark.

出版信息

J Affect Disord. 2020 Apr 1;266:215-222. doi: 10.1016/j.jad.2020.01.078. Epub 2020 Jan 20.

Abstract

BACKGROUND

Previous research suggests that job insecurity is associated with poor mental health, but research examining how different aspects of job insecurity relate to clinical measures of poor mental health are lacking. We aimed to investigate the association between cognitive and affective job insecurity and incident purchases of psychotropic drugs.

METHODS

We included 14,586 employees participating in the Swedish Longitudinal Occupational Survey of Health (SLOSH), who answered questions on cognitive and/or affective job insecurity in 2010, 2012 or 2014. Respondents were followed in the Swedish Prescribed Drug Register (2.5 years on average). We investigated the association between job insecurity and incident psychotropic drugs with marginal structural Cox models.

RESULTS

Affective job insecurity was associated with an increased risk of purchasing any psychotropic drugs (Hazard Ratio (HR) 1.40 (95% Confidence Interval (CI) 1.04-1.89)) while cognitive job insecurity was not (HR 1.15 (95% CI 0.92-1.43)). Cognitive and affective job insecurity were both associated with antidepressants, affective job insecurity with anxiolytics, but no association was found with sedatives. Women and younger workers seemed to have higher risk compared to men and older workers, but differences were not statistically significant.

LIMITATIONS

Although job insecurity and psychotropic drugs were assessed through independent sources and several covariates were considered, unmeasured confounding cannot be ruled out.

CONCLUSIONS

The findings support that affective job insecurity is a risk factor for psychotropic drug treatment, that it may be relevant to distinguish between different types of job insecurity, and to consider sex and age as moderating factors.

摘要

背景

先前的研究表明,工作不安全感与心理健康状况不佳有关,但缺乏研究来检验工作不安全感的不同方面与心理健康不良的临床测量指标之间的关系。我们旨在调查认知和情感工作不安全感与精神药物购买事件之间的关联。

方法

我们纳入了 14586 名参与瑞典纵向职业健康调查(SLOSH)的员工,他们在 2010 年、2012 年或 2014 年回答了关于认知和/或情感工作不安全感的问题。被随访者在瑞典处方药物登记处(平均 2.5 年)。我们使用边缘结构 Cox 模型调查了工作不安全感与精神药物购买事件之间的关联。

结果

情感工作不安全感与购买任何精神药物的风险增加相关(危险比 (HR) 1.40(95%置信区间 (CI) 1.04-1.89)),而认知工作不安全感则没有(HR 1.15(95% CI 0.92-1.43))。认知和情感工作不安全感都与抗抑郁药有关,情感工作不安全感与抗焦虑药有关,但与镇静剂无关。与男性和老年工人相比,女性和年轻工人的风险似乎更高,但差异无统计学意义。

局限性

尽管工作不安全感和精神药物是通过独立的来源评估的,并且考虑了几个协变量,但不能排除未测量的混杂因素。

结论

研究结果支持情感工作不安全感是精神药物治疗的危险因素,可能需要区分不同类型的工作不安全感,并考虑性别和年龄作为调节因素。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验