Farrell Lara J, Lavell Cassie, Baras Eden, Zimmer-Gembeck Melanie J, Waters Allison M
School of Applied Psychology, Griffith University, Gold Coast Campus, Southport, Qld, Australia, 4222.
School of Applied Psychology, Griffith University, Gold Coast Campus, Southport, Qld, Australia, 4222.
J Affect Disord. 2020 Apr 1;266:585-594. doi: 10.1016/j.jad.2020.01.144. Epub 2020 Jan 31.
Paediatric obsessive-compulsive disorder (OCD) is highly comorbid with other psychological disorders, including attention deficit/hyperactivity disorder (ADHD). Preliminary evidence suggests that youth with comorbid OCD and ADHD may experience greater impairments than children with other comorbidities; however, there is limited research examining the clinical expression and treatment response of these youth.
Youth (7 to 17 years) with a primary diagnosis of OCD and comorbid ADHD (n = 40) were compared a sample of age and gender matched youth with OCD and other comorbidity (without ADHD, n = 40). The study investigated symptoms, severity, functioning, comorbidity, family accommodation, in addition to parental psychopathology and rearing styles. Treatment response was investigated at post-treatment and six-month follow-up.
Youth with comorbid OCD and ADHD had fewer sexual obsessions, higher rates of comorbidity, poorer executive functioning and higher family impairment. Families of comorbid youth engaged in significantly more accommodation and reported more negative rearing. Finally, comorbid youth were significantly less likely to be responders or remitters at post-treatment.
Limitations include the cross-sectional design, relatively small clinical sample, and lack of an experimental control group of youth with ADHD without OCD. Current approaches to treatment may be improved for youth with comorbid OCD and ADHD by addressing cooccurring anxiety, behavioural difficulties, and maladaptive family accommodation and rearing. Moreover, given pronounced deficits in executive function, these youth may require a stronger initial dose of CBT to achieve an adequate response.
小儿强迫症(OCD)与其他心理障碍高度共病,包括注意力缺陷多动障碍(ADHD)。初步证据表明,患有强迫症和多动症共病的青少年可能比患有其他共病的儿童经历更大的损害;然而,研究这些青少年的临床表现和治疗反应的研究有限。
将初步诊断为强迫症和多动症共病的青少年(7至17岁,n = 40)与年龄和性别匹配的患有强迫症和其他共病(无多动症,n = 40)的青少年样本进行比较。该研究调查了症状、严重程度、功能、共病情况、家庭适应性,以及父母的精神病理学和养育方式。在治疗后和六个月随访时调查治疗反应。
患有强迫症和多动症共病的青少年性强迫观念较少,共病率较高,执行功能较差,家庭损害较大。共病青少年的家庭参与了更多的适应性行为,并报告了更多负面的养育方式。最后,共病青少年在治疗后成为反应者或缓解者的可能性显著降低。
局限性包括横断面设计、相对较小的临床样本,以及缺乏没有强迫症的多动症青少年的实验对照组。对于患有强迫症和多动症共病的青少年,目前的治疗方法可能需要通过解决同时出现的焦虑、行为困难以及适应不良的家庭适应性和养育方式来改进。此外,鉴于执行功能存在明显缺陷,这些青少年可能需要更强的初始剂量的认知行为疗法才能获得足够的反应。