Department of Otolaryngology, Head and Neck Surgery, Tottori University, 36-1, Nishi-Cho, Yonago, Tottori 683-8504, Japan.
Department of Otolaryngology, Head and Neck Surgery, Tottori University, 36-1, Nishi-Cho, Yonago, Tottori 683-8504, Japan.
Auris Nasus Larynx. 2020 Dec;47(6):1074-1078. doi: 10.1016/j.anl.2020.01.010. Epub 2020 Feb 11.
Leiomyomas are benign tumors with smooth muscle differentiation that occur most frequently in the uterine myometrium. They are uncommon in the head and neck region. We report a rare case of tongue base leiomyoma successfully resected with transoral endoscopic surgery. A 14-year-old male was found to have a tongue base tumor. The tumor located in the right tongue base. It had a smooth surface and no deep invasion. The tumor was resected with transoral videolaryngoscopic surgery. There were no serious adverse events requiring further intervention. Histologically, the tumor was composed of densely cellular fascicles of spindle-shaped cells with smooth muscle differentiation with diffuse and intense reactivity for α-smooth muscle actin, desmin, calponin, and anaplastic lymphoma kinase on immunohistochemistry. After careful consideration of the differential diagnosis, the tumor was diagnosed a smooth muscle tumor, mostly consistent with leiomyoma. This is the first report of leiomyoma arising from the tongue base that was completely resected by transoral videolaryngoscopic surgery without adverse events. For tongue base tumors, endoscopic transoral surgery can be considered as an option for complete resection without impairment of postoperative function.
平滑肌瘤是具有平滑肌分化的良性肿瘤，最常发生于子宫子宫肌层。它们在头颈部很少见。我们报告了一例成功通过经口内镜手术切除的舌根平滑肌瘤的罕见病例。一名 14 岁男性被发现舌根部有肿瘤。肿瘤位于右舌根。表面光滑，无深部浸润。肿瘤通过经口视频喉镜手术切除。没有需要进一步干预的严重不良事件。组织学上，肿瘤由密集的梭形细胞束组成，具有平滑肌分化，免疫组织化学显示α-平滑肌肌动蛋白、结蛋白、钙调蛋白和间变性淋巴瘤激酶弥漫且强烈反应。在仔细考虑鉴别诊断后，该肿瘤被诊断为平滑肌肉瘤，主要为平滑肌瘤。这是首例舌根平滑肌瘤完全经口内镜手术切除且无不良事件的报告。对于舌根肿瘤，内镜经口手术可以作为一种选择，以实现无功能损害的完全切除。
