Yaslikaya Serhat, Kizilay Ahmet, Şamdanci Emine
Department of Otorhinolaryngology, Adiyaman University Training and Research Hospital, Adiyaman.
Department of Otorhinolaryngology, Inönü University, Turgut Özal Medicine Center.
J Craniofac Surg. 2020 Jun;31(4):e409-e411. doi: 10.1097/SCS.0000000000006416.
Schwannoma is a benign slow growing nerve sheath tumor that is typically encapsulated and composed of well-differentiated schwann cells. Schwannomas may take origin from different nerves such as cranial, spinal nerves, and the sympathetic chain. Approximately 25% to 45% of all occur in the head and neck only 1% of them are located in the oral cavity. However, it is quite rare to for schwannomas to form on the tongue base. Ancient schwannoma is the rarest, and also extremely rare in oropharynx. A 32-year-old female patient was admitted to our clinic with complaints of hoarseness, difficulty in swallowing, throat pain, snoring, and dyspnea. In examination, a smooth surfaced circumscribed mass, which originated from the tongue base was observed. In the magnetic resonance imaging, a 4.5 × 3 cm sized tongue base mass which narrowed the upper airway was detected. An endoscopic transoral excisional biopsy was performed. The histopathological diagnosis was determined as ancient schwannoma. The use of the endoscopic transoral approach can be suitable to protect the important anatomical structures, functions, and reduce the complications and esthetic concerns for the resection of tongue base schwannomas.
神经鞘瘤是一种生长缓慢的良性神经鞘肿瘤，通常有包膜，由分化良好的施万细胞组成。神经鞘瘤可起源于不同神经，如颅神经、脊神经和交感神经链。所有神经鞘瘤中约25%至45%仅发生在头颈部，其中只有1%位于口腔。然而，舌根部形成神经鞘瘤相当罕见。陈旧性神经鞘瘤最为罕见，在口咽也极为少见。一名32岁女性患者因声音嘶哑、吞咽困难、咽痛、打鼾和呼吸困难等症状入院。检查时，发现一个起源于舌根部、表面光滑、边界清晰的肿块。磁共振成像显示，一个大小为4.5×3厘米的舌根部肿块使上呼吸道变窄。进行了内镜经口切除活检。组织病理学诊断为陈旧性神经鞘瘤。内镜经口入路适用于保护重要解剖结构和功能，减少舌根部神经鞘瘤切除的并发症和美观问题。
