École de réadaptation, Faculté de médecine, Université de Montréal, Montreal, Quebec, H3C 3J7, Canada; Centre de recherche, CHU Sainte-Justine, Montreal, Quebec, H1T 1C5, Canada.
Département de kinésiologie, Faculté de médecine, Université Laval, Quebec, Quebec, G1V 0A6, Canada; Centre interdisciplinaire de recherche en réadaptation et intégration sociale (CIRRIS), Quebec, Quebec, G1M 2S8, Canada.
Neurosci Lett. 2020 Mar 23;722:134836. doi: 10.1016/j.neulet.2020.134836. Epub 2020 Feb 11.
Adolescent idiopathic scoliosis (AIS) is a multifactorial disorder characterized by a tridimensional deformation of the spine. AIS pathophysiology is still unclear and its aetiology is unknown. Results from several studies revealed balance control alterations in adolescents with AIS suggesting cortical sensorimotor processing impairments. Studies assessing cortical activity involved in balance control revealed an increase in alpha peak frequency (APF), which is a neurophysiological marker of thalamo-cortical transmission, related to a more challenging balance task. The objective of this study is to assess APF of adolescents with AIS during balance control in upright standing posture using electroencephalography (EEG). EEG was recorded in 16 girls with AIS and 15 control girls in normal standing posture on a force platform. The participants stood upright for 2 min with eyes open and 2 min with eyes closed. Fast Fourier transformations of EEG data were calculated to obtain APF. Balance performances were assessed through the area of an ellipse covering the center of pressure (COP) displacement and the root mean square value of the COP velocity. Compared to the control group, APF was higher in the AIS group at central, frontal, parietal and occipital regions. Further, COP analyses did not reveal any difference between AIS and control groups. A higher APF may indicate the need for increased cortical processing to maintain balance control in normal upright standing in adolescents with AIS compared to healthy controls. We suggest that this may be a compensatory strategy to overcome balance control challenges.
青少年特发性脊柱侧凸（AIS）是一种多因素疾病，其特征是脊柱的三维变形。AIS 的病理生理学仍然不清楚，其病因尚不清楚。多项研究的结果表明，AIS 青少年的平衡控制能力发生改变，提示皮质感觉运动处理受损。评估涉及平衡控制的皮质活动的研究表明，阿尔法峰值频率（APF）增加，这是丘-皮质传递的神经生理标志物，与更具挑战性的平衡任务有关。本研究旨在使用脑电图（EEG）评估青少年特发性脊柱侧凸患者在直立站立姿势下平衡控制时的 APF。在正常站立姿势下，16 名 AIS 女孩和 15 名对照组女孩在力平台上进行了 EEG 记录。参与者睁眼站立 2 分钟，闭眼站立 2 分钟。对 EEG 数据进行快速傅里叶变换以获得 APF。通过覆盖压力中心（COP）位移的椭圆区域和 COP 速度的均方根值来评估平衡表现。与对照组相比，AIS 组在中央、额部、顶叶和枕叶区域的 APF 更高。此外，COP 分析并未显示 AIS 和对照组之间存在任何差异。与健康对照组相比，AIS 青少年在正常直立站立时，APF 较高可能表明需要增加皮质处理以维持平衡控制。我们认为这可能是一种补偿策略，可以克服平衡控制挑战。
