Changes in intestinal microbiota and disease resistance following dietary postbiotic supplementation in rainbow trout (Oncorhynchus mykiss).

This experimental study was aimed to investigate whether the dietary supplementation of a postbiotic obtained as a food product fermented with two lactic acid bacteria could induce changes in the intestinal microbiota and prevent the development of Lactococcus garvieae infection in rainbow trout (Oncorhynchus mykiss). After 30 days of dietary postbiotic supplementation, bacterial community composition and structure was significantly different between the treated and control groups. A higher bacterial diversity and richness in the intestinal samples was found in treated fish, as compared to those samples from untreated fish. Dietary postbiotic supplementation also conferred increased protection against L. garvieae infection. These findings suggest that the establishment of a beneficial microbiota is essential to prevent diseases or protect the host from foreign agents.