VA San Diego Healthcare System, San Diego, CA 92161, USA; Department of Psychiatry, University of California, San Diego, CA 92093, USA.
VA San Diego Healthcare System, San Diego, CA 92161, USA; Department of Psychiatry, University of California, San Diego, CA 92093, USA; VA Center of Excellence for Stress and Mental Health, San Diego, CA 92161, USA; National Center for PTSD, White River Junction, VT 05009, USA.
Addict Behav. 2020 Jun;105:106313. doi: 10.1016/j.addbeh.2020.106313. Epub 2020 Jan 17.
Although veterans are at increased risk of alcohol use disorder (AUD) relative to civilians, few longitudinal studies have examined both risk and protective factors that influence the development of AUD. This study aimed to identify risk and protective factors that contribute to incident AUD.
Data were analyzed from the National Health and Resilience in Veterans Study (NHRVS), a nationally representative, prospective cohort study of U.S. veterans. The sample included 1,770 veterans who did not meet criteria for lifetime AUD at Wave 1 and completed at least one follow-up assessment over a 7-year period. Veterans completed self-report measures to assess for risk and protective factors. A multivariable binary logistic regression analysis was conducted to examine baseline factors associated with incident AUD.
A total of 5.9% of veterans without AUD at Wave 1 developed AUD in the 7-year follow-up period. Adult sexual trauma, greater severity of anxious arousal symptoms of PTSD, lifetime history of drug and nicotine use disorders, and higher alcohol consumption at Wave 1 were independently associated with incident AUD. Lifetime drug use disorder (75.9%) and higher alcohol consumption (22.1%) explained the most variance in incident AUD.
Approximately 6% of veterans without AUD at Wave 1 developed AUD over a 7-year period. Lifetime drug use disorder and greater alcohol consumption at baseline, as well as trauma-related characteristics (i.e., adult sexual trauma, anxious arousal symptoms), were associated with increased risk of developing AUD. Future research should examine whether treatment of drug use disorder and PTSD symptoms in at-risk veterans may help mitigate risk of developing AUD in this population.
与平民相比,退伍军人酗酒障碍(AUD)的风险增加,但很少有纵向研究探讨影响 AUD 发展的风险和保护因素。本研究旨在确定导致 AUD 发生的风险和保护因素。
数据分析来自美国退伍军人国家健康和复原力研究(NHRVS),这是一项针对美国退伍军人的全国代表性前瞻性队列研究。样本包括 1770 名在第 1 波时未达到终生 AUD 标准且在 7 年期间至少完成一次随访评估的退伍军人。退伍军人完成自我报告评估以评估风险和保护因素。采用多变量二项逻辑回归分析来检验与 AUD 发生相关的基线因素。
在第 1 波时无 AUD 的退伍军人中,有 5.9%在 7 年随访期间发展为 AUD。第 1 波时成人性创伤、更严重的 PTSD 焦虑觉醒症状、终生药物和尼古丁使用障碍史以及更高的酒精摄入量与 AUD 的发生独立相关。终生药物使用障碍(75.9%)和更高的酒精摄入量(22.1%)解释了 AUD 发生的最大差异。
大约 6%的第 1 波时无 AUD 的退伍军人在 7 年内发展为 AUD。终生药物使用障碍和基线时更高的酒精摄入量,以及与创伤相关的特征(即成人性创伤、焦虑觉醒症状),与 AUD 发生风险增加相关。未来的研究应探讨是否对高危退伍军人进行药物使用障碍和 PTSD 症状的治疗可能有助于减轻该人群发生 AUD 的风险。