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手持式稀疏探头光声超声容积成像:实验概念验证研究。

Sparse hand-held probe for optoacoustic ultrasound volumetric imaging: an experimental proof-of-concept study.

出版信息

Opt Lett. 2020 Feb 15;45(4):885-888. doi: 10.1364/OL.384002.

Abstract

We present an experimental proof-of-concept study on the performance of a sparse segmented annular array for optoacoustic imaging. A capacitive micromachined ultrasonic transducer was equipped with a negatively focused acoustic lens and scanned in an annular fashion to exploit the performance of the sparse array geometry proposed in our recent numerical studies [Biomed. Opt. Express10, 1545 (2019)BOEICL2156-708510.1364/BOE.10.001545; J. Biomed. Opt.23, 025004 (2018)JBOPFO1083-366810.1117/1.JBO.23.2.025004]. A dedicated water tank was made using a 3D printer for light delivery and mounting the sample. A phantom experiment was carried out to showcase the possibility of full-field optoacoustic ultrasound (OPUS) imaging and confirm the earlier numerical results. This proof of concept opens the door towards a prototype of OPUS imaging for (pre-) clinical studies.

摘要

我们提出了一项稀疏分段环形阵列在光声成象性能的实验验证研究。一个电容式微机械超声换能器配备了负聚焦声透镜,并以环形方式扫描,以利用我们最近的数值研究中提出的稀疏阵列几何形状的性能[生物医学光学快报 10,1545(2019)BOEICL2156-708510.1364/BOE.10.001545;生物医学光学 23,025004(2018)JBOPFO1083-366810.1117/1.JBO.23.2.025004]。一个专门的水箱是使用 3D 打印机制作的,用于提供光线和安装样品。进行了一个体模实验,以展示全视野光声超声(OPUS)成像的可能性,并证实了早期的数值结果。这一概念验证为(临床前)临床研究的 OPUS 成像原型打开了大门。

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