Division of Cardiology (S.C., J.E.W., K.L.G., C.W.Y., S.S.K.), Northwestern University Feinberg School of Medicine.
Department of Preventive Medicine (R.M., S.S.K.), Northwestern University Feinberg School of Medicine.
Circ Heart Fail. 2020 Feb;13(2):e006587. doi: 10.1161/CIRCHEARTFAILURE.119.006587. Epub 2020 Feb 14.
The location of death is an important component of end-of-life care. However, contemporary trends in the location of death for cardiovascular deaths related to heart failure (CV-HF) and comparison to cancer deaths have not been fully examined.
We analyzed data from the Centers for Disease Control and Prevention's Control Wide-Ranging Online Data for Epidemiologic Research database between 2003 and 2017 to identify location of death for CV-HF and cancer deaths. The proportions of deaths that occurred in a hospice facility, home, and medical facility were tested for trends using linear regression. Odds ratios were calculated to determine the odds of death occurring in a hospice facility or home (versus a medical facility) stratified by sex and race.
We identified 2 940 920 CV-HF and 8 852 066 cancer deaths. Increases were noted in the proportion of CV-HF deaths in hospice facilities (0.2% to 8.2%; <0.001) and at home (20.6% to 30.7%; <0.001), whereas decreases were noted in the proportion of deaths in medical facilities (44.5% to 31.0%; <0.001) and nursing homes (30.8% to 25.7%; <0.001). The odds of dying in a hospice facility (odds ratio, 1.79 [1.75-1.82]) or at home (odds ratio, 1.55 [1.53-1.56]) versus a medical facility was higher for whites versus blacks. The rate of increase in proportion of deaths in hospice facilities was higher for cancer deaths (β=1.05 [95% CI, 0.97-1.12]) than for CV-HF deaths (β=0.61 [95% CI, 0.58-0.64]).
The proportion of CV-HF deaths occurring in hospice facilities is increasing but remains low. Disparities are noted whereby whites are more likely to die in hospice facilities or at home versus medical facilities compared with blacks. More research is needed to determine end-of-life preferences for patients with HF and identify the basis for these differences in location of death.
死亡地点是临终关怀的一个重要组成部分。然而,心力衰竭(CV-HF)相关心血管死亡的死亡地点的当代趋势以及与癌症死亡的比较尚未得到充分研究。
我们分析了疾病控制与预防中心的控制广泛在线数据进行流行病学研究数据库在 2003 年至 2017 年间,以确定 CV-HF 和癌症死亡的死亡地点。使用线性回归测试了在临终关怀机构、家庭和医疗机构中死亡的比例趋势。计算了比值比,以确定按性别和种族分层,在临终关怀机构或家庭(而非医疗机构)中死亡的可能性。
我们确定了 2940920 例 CV-HF 和 8852066 例癌症死亡。在临终关怀机构(0.2%至 8.2%;<0.001)和家中(20.6%至 30.7%;<0.001)的 CV-HF 死亡比例增加,而在医疗机构(44.5%至 31.0%;<0.001)和疗养院(30.8%至 25.7%;<0.001)的死亡比例下降。与在医疗机构相比,白人在临终关怀机构(比值比,1.79[1.75-1.82])或在家中(比值比,1.55[1.53-1.56])死亡的可能性更高。与 CV-HF 死亡相比,癌症死亡的死亡比例在临终关怀机构中的增加速度更高(β=1.05[95%置信区间,0.97-1.12])。
在临终关怀机构中发生的 CV-HF 死亡比例正在增加,但仍然很低。注意到,与黑人相比,白人更有可能在临终关怀机构或家中而不是医疗机构中死亡。需要进一步研究以确定 HF 患者的临终关怀偏好,并确定死亡地点差异的基础。