Martyn Emily, Heward Jack, Herbert Rachel
Microbiology, North Middlesex University Hospital NHS Trust, London, UK
North Middlesex University Hospital NHS Trust, London, London, UK.
BMJ Case Rep. 2020 Feb 13;13(2):e233125. doi: 10.1136/bcr-2019-233125.
is a Gram-negative zoonosis which occasionally infects humans via ingestion of contaminated food and water, and typically causes a self-limiting gastrointestinal tract infection. Patients who are immunocompromised, have haemochromatosis or liver cirrhosis are more likely to develop serious complications such as bacteraemia. We present the case of a 76-year-old man with fever and an acutely tender, swollen right knee. Blood cultures were positive for , and 16s ribosomal PCR analysis of his knee aspirate confirmed septic arthritis. He was treated with intravenous ceftriaxone and made an excellent recovery following knee washout. Interestingly, our patient did not have any of the classic risk factors described in the literature, or history of exposure to the pathogen to explain his diagnosis. To our knowledge, this is only the second confirmed case of bacteraemia with septic arthritis, and the first to involve the knee joint.
是一种革兰氏阴性人畜共患病，偶尔通过摄入受污染的食物和水感染人类，通常引起自限性胃肠道感染。免疫功能低下、患有血色素沉着症或肝硬化的患者更有可能发生严重并发症，如菌血症。我们报告一例76岁男性患者，有发热症状，右膝急性压痛、肿胀。血培养结果为阳性，对其膝关节抽出液进行的16s核糖体PCR分析证实为化脓性关节炎。他接受了静脉注射头孢曲松治疗，膝关节冲洗后恢复良好。有趣的是，我们的患者没有文献中描述的任何典型危险因素，也没有接触病原体的病史来解释他的诊断。据我们所知，这是第二例确诊的伴有化脓性关节炎的菌血症病例，也是第一例累及膝关节的病例。
