Baer G M
Viral and Rickettsial Zoonoses Branch, Centers for Disease Control, Lawrenceville, Georgia 30246-0363.
Rev Infect Dis. 1988 Nov-Dec;10 Suppl 4:S644-8. doi: 10.1093/clinids/10.supplement_4.s644.
The vaccination of wild animals against rabies was first attempted in 1962 after the repeated failure of poisoning or trapping to control the movement of the disease in these species. The initial requirements of such a vaccine were that it be efficacious and inexpensive, that it allow animals to immunize themselves, and that it not cause vaccine rabies in the target species. Foxes were chosen for research purposes because they are a problem species and are exquisitely susceptible to rabies. The first successful laboratory studies with attenuated vaccine came in 1971, and the first field trial (successful) was carried out in Switzerland beginning in 1978. Other species have not yet been immunized in the field.
在通过投毒或诱捕控制狂犬病在野生动物中的传播屡屡失败后，1962年首次尝试给野生动物接种狂犬病疫苗。这种疫苗的最初要求是有效且廉价，能让动物自行免疫，且不会在目标物种中引发疫苗性狂犬病。选择狐狸进行研究是因为它们是问题物种，且对狂犬病极为易感。1971年首次在实验室对减毒疫苗进行了成功研究，1978年在瑞士开始了首次（成功的）现场试验。其他物种尚未在野外进行免疫接种。
