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腰椎管狭窄症患者睡眠障碍的患病率及危险因素分析

Prevalence of sleep disturbance in patients with lumbar spinal stenosis and analysis of the risk factors.

作者信息

Kim Jihye, Park Jihun, Kim Seok Woo, Oh Jae-Keun, Park Moon Soo, Kim Young-Woo, Kim Tae-Hwan

机构信息

Division of Infection, Department of Pediatrics, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, 150, Seongan-ro, Gangdong-gu, Seoul 05355, Republic of Korea.

Department of Orthopedics, Spine Center, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, 22, Gwanpyeong-ro, 170 beon-gil, Dongan-gu, Anyang-si, Gyeonggi-do 14068, Republic of Korea.

出版信息

Spine J. 2020 Aug;20(8):1239-1247. doi: 10.1016/j.spinee.2020.02.008. Epub 2020 Feb 13.

DOI:10.1016/j.spinee.2020.02.008
PMID:32061837
Abstract

BACKGROUND CONTEXT

Although sleep quality is indispensable for good quality of life, it has not been properly measured or treated in patients with lumbar spinal stenosis (LSS). Studies that investigate the prevalence of sleep disturbances and identify high-risk patients are essential to help understand mechanisms of sleep disturbance in patients with LSS, develop multimodal treatment strategies, and eventually improve the clinical outcome for LSS.

PURPOSE

The purpose of the study was to investigate the prevalence and status of sleep disturbance in patients with LSS and understand its mechanism by identifying the risk factors.

STUDY DESIGN/SETTING: Cross-sectional study.

PATIENT SAMPLE

Patients diagnosed with LSS.

OUTCOME MEASURES

Pittsburgh sleep quality index (PSQI).

METHODS

A study was performed on patients diagnosed with LSS. Sleep disturbance was evaluated using the PSQI. Clinical and radiologic risk factors of sleep disturbance were investigated by comparing its presence and absence in patients with LSS. Multivariate logistic regression analysis was conducted to identify significant risk factors related to sleep disturbance.

RESULTS

A total of 230 patients with LSS were analyzed in our study, 141 of whom (61.3%) were women, and the average age was 67.7 years. Sleep disturbance (PSQI score≥6) was identified in 66.1% of the patients (152 out of 230). After a multivariate analysis, sleep disturbance was consistently associated with the female sex, a negative score on the depression scale, and a severe foraminal-type stenosis. Oswestry disability index, visual analogue pain scale, and presence of nocturnal pain were not independently associated with sleep disturbance.

CONCLUSIONS

This study identified potential high-risk groups for sleep disturbance among patients with LSS. Proper caution and evaluation for these patients, along with further studies about their treatment outcomes, are required.

摘要

背景

尽管睡眠质量对于良好的生活质量不可或缺,但腰椎管狭窄症(LSS)患者的睡眠质量尚未得到妥善评估或治疗。开展研究以调查睡眠障碍的患病率并识别高危患者,对于理解LSS患者睡眠障碍的机制、制定多模式治疗策略以及最终改善LSS的临床结局至关重要。

目的

本研究旨在调查LSS患者睡眠障碍的患病率和状况,并通过识别风险因素来了解其机制。

研究设计/地点:横断面研究。

患者样本

确诊为LSS的患者。

结局指标

匹兹堡睡眠质量指数(PSQI)。

方法

对确诊为LSS的患者进行了一项研究。使用PSQI评估睡眠障碍。通过比较LSS患者中睡眠障碍的有无,调查睡眠障碍的临床和影像学风险因素。进行多因素逻辑回归分析以识别与睡眠障碍相关的显著风险因素。

结果

本研究共分析了230例LSS患者,其中141例(61.3%)为女性,平均年龄为67.7岁。66.1%的患者(230例中的152例)存在睡眠障碍(PSQI评分≥6)。多因素分析后,睡眠障碍与女性性别、抑郁量表负评分以及严重的椎间孔型狭窄始终相关。Oswestry功能障碍指数、视觉模拟疼痛量表和夜间疼痛的存在与睡眠障碍无独立相关性。

结论

本研究确定了LSS患者中睡眠障碍的潜在高危人群。需要对这些患者进行适当的关注和评估,并进一步研究其治疗效果。

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