Department of Plant Systems Biology, VIB, B-9052 Ghent, Belgium; Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Ghent, Belgium; Bioinformatics Institute Ghent, Ghent University, 9052 Ghent, Belgium.
Department of Plant Systems Biology, VIB, B-9052 Ghent, Belgium; Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Ghent, Belgium; Bioinformatics Institute Ghent, Ghent University, 9052 Ghent, Belgium.
Curr Opin Plant Biol. 2020 Apr;54:42-48. doi: 10.1016/j.pbi.2019.12.008. Epub 2020 Feb 13.
The availability of genome sequences, genome-wide assays of transcription factor binding, and accessible chromatin maps have unveiled gene regulatory landscapes in plants. This understanding has ushered in comparative gene regulatory network studies that assess network rewiring between species, across time, and between biological tissues. Comparisons of cis-regulatory elements across the plant kingdom have uncovered examples of conserved sequences, but also of divergence, indicating that selective pressures can vary in different plant families. Transcription factor duplication, followed by spatiotemporal expression divergence of the duplicates, also appears to be a key mechanism of network evolution. Here, we review recent literature describing the regulation of gene expression in plants, and how comparative studies provide insights into how these regulatory interactions change and lead to gene regulatory network rewiring.
基因组序列的可用性、转录因子结合的全基因组分析以及可及染色质图谱揭示了植物中的基因调控景观。这种理解开创了比较基因调控网络研究，评估了物种之间、时间和生物组织之间的网络重连。对整个植物界的顺式调控元件的比较揭示了保守序列的例子，但也有分歧的例子，表明选择压力在不同的植物科中可能不同。转录因子复制，随后是重复的时空表达分歧，似乎也是网络进化的关键机制。在这里，我们回顾了描述植物中基因表达调控的最新文献，以及比较研究如何提供关于这些调控相互作用如何变化并导致基因调控网络重连的见解。
