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抑郁症患者因自杀观念或自杀行为住院后的再住院频率。

Frequency of rehospitalization after hospitalization for suicidal ideation or suicidal behavior in patients with depression.

作者信息

Cepeda M Soledad, Schuemie Martijn, Kern David M, Reps Jenna, Canuso Carla

机构信息

Epidemiology Dept. Janssen Research and Development, 1125 Trenton Harbourton Rd., Titusville, NJ 08560.

Epidemiology Dept. Janssen Research and Development, 1125 Trenton Harbourton Rd., Titusville, NJ 08560.

出版信息

Psychiatry Res. 2020 Jan 28;285:112810. doi: 10.1016/j.psychres.2020.112810.

DOI:10.1016/j.psychres.2020.112810
PMID:32062326
Abstract

This study sought to: 1. determine the frequency of rehospitalization with diagnosis of suicidal ideation or suicide attempt (SI/SA) within a year and how often patients had multiple rehospitalizations; 2. identify the time period for which the risk of rehospitalization is highest; and 3. determine the characteristics of patients with multiple rehospitalizations. We conducted a retrospective cohort study of adults with depression using 4 US health claims databases. We defined hospitalization as an inpatient or emergency room visit with codes indicating a suicide attempt or suicidal thoughts using a validated algorithm. Rates of rehospitalization with SI or SA were analyzed together and separately, including multiple re-hospitalizations with SI/SA. Across all databases 121,065 patients were hospitalized with a diagnosis of SI/SA. Rates of rehospitalization within a year ranged from 7.96% to 11.24%. The risk of rehospitalization with SI/SA is highest during the first month. Nearly 50% of rehospitalizations occurred within 3 months after initial hospitalization. Patients with rehospitalization(s) had more anxiety disorders, sleep disorders and substance use disorders than patients without. Among patients with depression hospitalized for SI/SA, rehospitalization for SI/SA within a year is not uncommon. Risk of rehospitalization with a diagnosis of SI/SA is highest during the first month.

摘要

本研究旨在

  1. 确定一年内因自杀意念或自杀未遂(SI/SA)诊断而再次住院的频率以及患者多次再次住院的频率;2. 确定再次住院风险最高的时间段;3. 确定多次再次住院患者的特征。我们使用4个美国医疗索赔数据库对成年抑郁症患者进行了一项回顾性队列研究。我们将住院定义为使用经过验证的算法,通过表明自杀未遂或自杀想法的编码进行的住院或急诊室就诊。对伴有SI或SA的再次住院率进行了综合和单独分析,包括伴有SI/SA的多次再次住院。在所有数据库中,121,065名患者因SI/SA诊断而住院。一年内的再次住院率在7.96%至11.24%之间。伴有SI/SA的再次住院风险在第一个月最高。近50%的再次住院发生在首次住院后的3个月内。有再次住院经历的患者比没有的患者有更多的焦虑症、睡眠障碍和物质使用障碍。在因SI/SA住院的抑郁症患者中,一年内因SI/SA再次住院并不罕见。伴有SI/SA诊断的再次住院风险在第一个月最高。

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