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希腊经济危机期间的死产:一项基于人群的研究。

Stillbirth in Greece during the years of economic crisis: a population-based study.

机构信息

First Department of Pediatrics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.

Department of Hygiene, Epidemiology and Medical Statistics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.

出版信息

Eur J Pediatr. 2020 Jul;179(7):1157-1166. doi: 10.1007/s00431-020-03588-6. Epub 2020 Feb 15.

Abstract

The recent economic crisis has been linked with declines in population health. Evidence on the impact of the crisis on stillbirth rates is scarce. The aim of this study was to assess trends of stillbirth rates in Greece during the pre-crisis (2004-2008) and crisis period (2009-2015) and explore risk factors. Nationwide data (n = 1,276,816 births; 5023 stillbirths) were used to assess rates and trends through Poisson and joinpoint regressions. Multivariable Poisson regressions by nationality were fitted. The overall annual stillbirth rate was 3.9/1000 births with higher rates among non-Greeks (5.0/1000) than Greeks (3.7/1000). Non-significant decreasing trends were noted for Greeks (- 0.5%, 95% confidence interval [CI] - 1.4, 0.4%) versus non-significant increasing trends in non-Greeks (1.4%, 95% CI - 0.5, 3.3%). After adjusting for possible confounders, the relative stillbirth risk (RR) increased during the crisis versus the pre-crisis period (RR 1.61, 95% CI 1.50, 1.74; RR 1.92, 95% CI 1.64, 2.26). Multiplicity, birth order, birth size, maternal education, marital status, and parental age were risk factors.Conclusions: Bidirectional stillbirth trends were observed among Greeks and non-Greeks, whereas the RR increased by 2-fold during the crisis. Persisting disparities require tailored employment of preventive measures ensuring optimal quality of the child's and maternal health.What is Known:• Stillbirth rate is a key population health indicator reflecting economic development and health care services within a population.• The recent economic crisis has been linked with declines in population health.What is New:• Economic crisis, ethnic minorities, and several modifiable factors seem to be significant determinants of stillbirth risk.

摘要

最近的经济危机与人口健康状况的下降有关。关于危机对死产率影响的证据很少。本研究的目的是评估希腊在危机前(2004-2008 年)和危机期间(2009-2015 年)的死产率趋势,并探讨风险因素。使用全国范围的数据(n=1276816 例分娩;5023 例死产),通过泊松和联合回归评估比率和趋势。按国籍拟合多变量泊松回归。总的年死产率为 3.9/1000 例,非希腊人(5.0/1000)的比率高于希腊人(3.7/1000)。希腊人(-0.5%,95%置信区间[CI] -1.4,0.4%)的趋势无显著下降,而非希腊人(1.4%,95%CI -0.5,3.3%)的趋势无显著上升。调整可能的混杂因素后,与危机前时期相比,危机期间的相对死产风险(RR)增加(RR 1.61,95%CI 1.50,1.74;RR 1.92,95%CI 1.64,2.26)。多胎、出生顺序、出生体重、母亲教育程度、婚姻状况和父母年龄是危险因素。

结论

希腊人和非希腊人之间观察到双向死产趋势,而危机期间 RR 增加了 2 倍。持续存在的差异需要有针对性地采取预防措施,确保儿童和产妇健康的最佳质量。

已知

  1. 死产率是反映人口经济发展和人口保健服务的关键人口健康指标。

  2. 最近的经济危机与人口健康状况的下降有关。

新内容

  1. 经济危机、少数民族和几个可改变的因素似乎是死产风险的重要决定因素。

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