Shaffer J W, Davy D T, Field G A, Bensusan J S, Kellis G J
Orthopaedic Research Laboratories, Wade Park Veterans Administration Hospital, Cleveland, Ohio.
Spine (Phila Pa 1976). 1988 Oct;13(10):1150-4. doi: 10.1097/00007632-198810000-00017.
Eleven canine experiments were performed to demonstrate the advantages of immediate vascular preservation in ribs used to fill a surgically created osseous gap bridging three vertebral bodies. In the five vascular rib grafts, mean blood flow was retained and measured at .101/ml/min/ml bone tissue. At autopsy 3 months post-operatively, vascularized grafts were more robust and hypertrophic. Mechanical testing in six stiffness modes confirmed the advantage of vascularized grafts. The experimental results indicate that vascularized grafts retain greater viability and better mechanical properties during graft incorporation. Providing a vascularized construct may be helpful in reconstructing large vertebral osseous gaps.
进行了11项犬类实验，以证明在用于填充跨越三个椎体的手术造成的骨间隙的肋骨中立即进行血管保留的优势。在5个带血管肋骨移植物中，平均血流得以保留，并测得为每毫升骨组织每分钟0.101毫升。术后3个月尸检时，带血管移植物更粗壮且肥大。在六种刚度模式下的力学测试证实了带血管移植物的优势。实验结果表明，带血管移植物在移植物融合过程中保持更高的活力和更好的力学性能。提供带血管结构可能有助于重建大的椎体骨间隙。
