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多巴胺联合呋塞米静脉输注对急性肾衰竭少尿期初期利尿作用的恢复

[Restoration of diuresis in the initial period of the oligoanuric stage of acute renal failure by dopamine-furosemide infusion].

作者信息

Razukas V A

出版信息

Ter Arkh. 1988;60(6):42-3.

PMID:3206367
Abstract

Dopamine-furosemide infusion was used in 31 patients with acute renal insufficiency (ARI) of various etiology in the initial period of the oligoanuric stage. The circulating blood volume was recovered in all the patients by infusion therapy and diuresis stimulation with mannitol and furanthril. The failure of these therapeutic measures was indicative of the presence of the oligoanuric stage of ARI. Dopamine was administered by intravenous drop infusion at a dose of 1-4 microgram/kg/min for 3-4 h followed by intravenous injection of 200 mg of furanthril. Dopamine infusion lasted for 4 more hours (even longer, if necessary), and furanthil during the 1st day was administered at a dose of 200 g every 6 h. The recovery of diuresis and renal function was observed in 13 patients (41.93%), diuresis was recovered but renal insufficiency remained (ARI oligoanuric type was transformed into polyuric type) in 14 patients (45.16%), no effect was noted in 4 patients (12.9%).

摘要

在少尿期初始阶段,对31例各种病因导致的急性肾功能不全(ARI)患者采用多巴胺 - 速尿静脉输注治疗。所有患者均通过输注治疗以及使用甘露醇和呋喃苯胺酸刺激利尿来恢复循环血容量。这些治疗措施无效表明处于ARI少尿期。多巴胺以1 - 4微克/千克/分钟的剂量静脉滴注3 - 4小时,随后静脉注射200毫克呋喃苯胺酸。多巴胺输注持续4小时以上(如有必要可更长),呋喃苯胺酸在第1天每6小时以200毫克的剂量给药。13例患者(41.93%)出现利尿和肾功能恢复,14例患者(45.16%)利尿恢复但肾功能不全仍存在(ARI少尿型转变为多尿型),4例患者(12.9%)无效果。

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