Sawhney Rahul, Volkmer Randy D, Cooper Barry
Department of Internal Medicine, Baylor University Medical CenterDallasTexas.
Texas A&M College of MedicineDallasTexas.
Proc (Bayl Univ Med Cent). 2019 Oct 25;33(1):62-64. doi: 10.1080/08998280.2019.1668720. eCollection 2020 Jan.
T-cell lymphomas comprise 10% to 15% of all lymphoid malignancies and affect precursor or mature T cells; the latter are referred to as peripheral T-cell lymphomas. We present a case of a subtype, angioimmunoblastic T-cell lymphoma, in which a patient previously treated with chemotherapy and autologous stem cell transplant relapsed with B symptoms and large pericardial/pleural effusions. Recurrent lymphoma was confirmed on pericardial tissue biopsy. Treatment was trialed with lenalidomide and the effusions resolved. Five months later she died from septic shock and multiorgan failure. Our case highlights the need for rapid evaluation of B symptoms and/or new effusions in patients with a known history of angioimmunoblastic T-cell lymphoma.
T细胞淋巴瘤占所有淋巴系统恶性肿瘤的10%至15%，累及前体或成熟T细胞；后者被称为外周T细胞淋巴瘤。我们报告一例血管免疫母细胞性T细胞淋巴瘤亚型病例，该患者先前接受化疗和自体干细胞移植治疗后，出现B症状及大量心包/胸腔积液复发。心包组织活检确诊为复发性淋巴瘤。试用来那度胺治疗后积液消退。五个月后，她死于感染性休克和多器官功能衰竭。我们的病例强调了对于有血管免疫母细胞性T细胞淋巴瘤已知病史的患者，需要快速评估B症状和/或新出现的积液。
