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盆腔内钙化性纤维性假瘤:1例报告并文献复习

Calcifying fibrous pseudotumor in the pelvic cavity: A case report and review of the literature.

作者信息

Ma Hong-Yu, Feng Ming-Tao, Hong Yong-Gang

机构信息

Department of Colorectal Surgery, Changhai Hospital, Shanghai 200433, P.R. China.

Department of Neurosurgery, Changhai Hospital, Shanghai 200433, P.R. China.

出版信息

Mol Clin Oncol. 2020 Mar;12(3):268-272. doi: 10.3892/mco.2020.1976. Epub 2020 Jan 13.

Abstract

Calcifying fibrous pseudotumors (CFPs) are rare benign lesions mostly occurring in the limbs, necks and gastrointestinal tracts of young adults. In the present study, we report the first known case of a pelvic CFP in China in a 67-year-old male patient. The solitary tumor had an extremely regular shape and was in the vicinity of the sigmoid colon. Surgical resection was performed and the tumor was histologically diagnosed as CFP. We reviewed 64 cases of CFPs and discussed the clinical features of this disease in China and other countries. We found that the CFPs were most common in patients aged 18-60 and often had no obvious symptoms. They were immunoreactive for vimentin and factor XIIIa, while negative for CD117 and S100. In China, CFPs were mostly identified in the stomach, possibly associated with Chinese eating. The pathogenesis of this disease remains unclear. More research is needed to confirm the present results.

摘要

钙化性纤维性假瘤(CFP)是一种罕见的良性病变,多见于年轻人的四肢、颈部和胃肠道。在本研究中,我们报告了中国首例67岁男性盆腔CFP病例。该孤立性肿瘤形状极为规则,位于乙状结肠附近。进行了手术切除,肿瘤经组织学诊断为CFP。我们回顾了64例CFP病例,并讨论了该疾病在中国和其他国家的临床特征。我们发现CFP在18至60岁的患者中最为常见,且通常无明显症状。它们对波形蛋白和因子ⅩⅢa呈免疫反应,而对CD117和S100呈阴性。在中国,CFP大多在胃中被发现,可能与中国人的饮食习惯有关。该疾病的发病机制尚不清楚。需要更多研究来证实目前的结果。

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