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儿童胰腺炎性肌纤维母细胞瘤:一例报告及文献复习

Inflammatory myofibroblastic tumors of the pancreas in children: A case report and literature review.

作者信息

Liu Hsien-Kuan, Lin Yung-Cheng, Yeh Ming-Lun, Chen Yaw-Sen, Su Yu-Tsun, Tsai Ching-Chung

机构信息

aDepartment of Pediatrics bDepartment of Pediatric Surgery cDepartment of Surgery, E-Da Hospital, I-Shou University, Yanchao District, Kaohsiung, Taiwan.

出版信息

Medicine (Baltimore). 2017 Jan;96(2):e5870. doi: 10.1097/MD.0000000000005870.

Abstract

INTRODUCTION

Inflammatory myofibroblastic tumors are an uncommon neoplasm, which are very rarely located in the pancreas. Clinically and radiologically, this rare pancreatic tumor presents as an abdominal mass lesion that mimics other pancreatic tumors, and should therefore be considered in the differential diagnosis of pancreatic tumors.

CLINICAL FINDINGS AND DIAGNOSIS

The 15-year-old boy complained of abdominal pain over the left upper quadrant with intermittent fever for 7 days. Abdominal sonography revealed one cystic lesion with a hyperechoic component in the left upper quadrant of the abdomen. Surgical excision was performed and postoperative findings indicated a pancreatic tail tumor. The pathology indicated inflammatory myofibroblastic tumors. To our knowledge, this patient is a unique case as the tumor was located in the pancreatic tail only, sparing the body.

INTERVENTIONS AND OUTCOMES

The patient underwent tumor resection and segmental resection of the transverse colon with simple closure. The patient had no evidence of disease recurrence at 3 years follow-up.

CONCLUSION

Inflammatory myofibroblastic tumors of the pancreas in children are extremely rare. Surgical excision is the standard treatment, and corticosteroids use in children need more large-scale studies.

摘要

引言

炎性肌纤维母细胞瘤是一种罕见的肿瘤,极少发生于胰腺。在临床和放射学上,这种罕见的胰腺肿瘤表现为腹部肿块病变,与其他胰腺肿瘤相似,因此在胰腺肿瘤的鉴别诊断中应予以考虑。

临床发现与诊断

一名15岁男孩主诉左上腹疼痛伴间歇性发热7天。腹部超声检查显示左上腹有一个含高回声成分的囊性病变。进行了手术切除,术后结果显示为胰尾肿瘤。病理结果为炎性肌纤维母细胞瘤。据我们所知,该患者是一个独特的病例,因为肿瘤仅位于胰尾,未累及胰体。

干预措施与结果

患者接受了肿瘤切除及横结肠节段性切除并一期缝合。随访3年,患者无疾病复发迹象。

结论

儿童胰腺炎性肌纤维母细胞瘤极为罕见。手术切除是标准治疗方法,儿童使用皮质类固醇需要更多大规模研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e235/5266186/50f14983ceba/medi-96-e5870-g001.jpg

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