Patel Chantal, Jones Elizabeth, Mudaliar Vivek, Paul Manju, Ismail Amir
Surgery, University Hospitals of North Midlands, Newcastle-under-Lyme, GBR.
Dermatopathology, University Hospitals of North Midlands, Newcastle-under-Lyme, GBR.
Cureus. 2020 Jan 12;12(1):e6635. doi: 10.7759/cureus.6635.
Neutrophilic eccrine hidradenitis (NEH) is a rare benign dermatological condition affecting the eccrine glands. The condition often occurs in response to chemotherapeutic agents in patients with acute myeloid leukemia (AML). However, cases of NEH are reported in patients with other malignancies and in those with non-malignant conditions. NEH is thought to result from the infiltration of neutrophils into the eccrine glands, resulting in erythematous papules and plaques on the skin. NEH is self-limiting and may resolve with cessation of the causative agent but can be treated symptomatically with steroids and analgesia. We report a case of NEH in a 52-year-old AML patient following the first cycle of chemotherapy. Following diagnosis, the patient was treated with a topical steroid and there was no recurrence. Alongside this, we uniquely present both clinical and histological images.
嗜中性小汗腺汗管炎（NEH）是一种累及小汗腺的罕见良性皮肤病。这种情况常发生于急性髓系白血病（AML）患者对化疗药物的反应中。然而，在其他恶性肿瘤患者和非恶性疾病患者中也有NEH病例的报道。NEH被认为是由于中性粒细胞浸润小汗腺，导致皮肤上出现红斑丘疹和斑块。NEH是自限性的，停用致病因素后可能会缓解，但也可用类固醇和镇痛进行对症治疗。我们报告了一例52岁AML患者在化疗第一周期后发生NEH的病例。诊断后，该患者接受了外用类固醇治疗，未再复发。除此之外，我们还独特地展示了临床和组织学图像。
