Giron Fanny, Alcantar Daniel
Internal Medicine, MacNeal Hospital, Berwyn, USA.
Cureus. 2020 Jan 12;12(1):e6637. doi: 10.7759/cureus.6637.
Carbohydrate antigen CA19-9 is a marker that has been used for the diagnosis of pancreatic and biliary malignancies, but it can also be present in benign conditions. Herein, we present the case of an 82-year-old female admitted for sepsis secondary to cholangitis, with a CA19-9 level of 12,838.3 U/mL. Initial imaging suggested a potential cholangiocarcinoma, but after multiple studies and biopsies, she was found to have a benign biliary stricture which triggered the cholangitis, explaining the increased CA19-9 levels. Clinicians should keep an open mind when assessing significantly elevated CA19-9 levels.
糖类抗原CA19-9是一种已用于诊断胰腺和胆道恶性肿瘤的标志物，但它也可能出现在良性疾病中。在此，我们报告一例82岁女性因胆管炎继发脓毒症入院，其CA19-9水平为12,838.3 U/mL。初始影像学检查提示可能为胆管癌，但经过多项检查和活检后，发现她患有良性胆管狭窄，这引发了胆管炎，解释了CA19-9水平升高的原因。临床医生在评估显著升高的CA19-9水平时应保持开放的思维。
