Université de Strasbourg, 8 allée Gaspard Monge, 67000, Strasbourg, France.
Adv Mater. 2020 May;32(20):e1906834. doi: 10.1002/adma.201906834. Epub 2020 Feb 16.
Fuel-driven reaction cycles are found in biological systems to control the assembly and disassembly of supramolecular materials such as the cytoskeleton. Fuel molecules can bind noncovalently to a self-assembling building block or they can react with it, resulting in covalent modifications. Overall the fuel can either switch the self-assembly process on or off. Here, a closer look is taken at artificial systems that mimic biological systems by making and breaking covalent bonds in a self-assembling motif. The different chemistries used so far are highlighted in chronological order and the pros and cons of each system are discussed. Moreover, the desired traits of future reaction cycles, their fuels, and waste management are outlined, and two chemistries that have not been explored up to now in chemically fueled dissipative self-assembly are suggested.
燃料驱动的反应循环存在于生物系统中，用于控制超分子材料（如细胞骨架）的组装和拆卸。燃料分子可以非共价结合到自组装的构建块上，也可以与其反应，导致共价修饰。总的来说，燃料可以打开或关闭自组装过程。在这里，我们更仔细地研究了通过在自组装模式中形成和断裂共价键来模拟生物系统的人工系统。按时间顺序突出显示了迄今为止使用的不同化学物质，并讨论了每个系统的优缺点。此外，概述了未来反应循环、其燃料和废物管理的理想特征，并提出了两种迄今为止在化学燃料耗散自组装中尚未探索的化学物质。
