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乌克兰基层医疗中心参与结核病治疗的情况。

Primary healthcare centers engagement in tuberculosis treatment in Ukraine.

作者信息

Geliukh Evgenia, Nabirova Dilyara, Davtyan Karapet, Yesypenko Svetlana, Zachariah Rony

机构信息

ICF "Alliance for Public Health", Kyiv, Ukraine.

US Centers for Disease Control and Prevention, Central Asia Regional Office, Almaty, Kazakhstan.

出版信息

J Infect Dev Ctries. 2019 Jul 31;13(7.1):83S-88S. doi: 10.3855/jidc.11292.

DOI:10.3855/jidc.11292
PMID:32065810
Abstract

INTRODUCTION

We assessed the influence of a result-based financing (RBF) model, which included incentives for Primary Healthcare facilities on TB treatment outcomes.

METHODOLOGY

We compared TB patients > 17 years and their treatment outcomes among those who did and did not benefit from RBF-model in 14 districts of Odeska oblast, Ukraine in 2017. Log-binomial regression was used to examine factors associated with being included in RBF-model.

RESULTS

Of 2,269 reported TB patients, 308 (14%) were included in RBF-model. Most patients in the RBF-model were from rural areas 229 (74%), unemployed 218 (71%), and HIV-infected 131 (43%). Individuals from urban areas (Adjusted risk ratio, ARR =0.9, 95% Confidence Interval, CI:0.89-0.94), having drug-resistant TB (ARR = 0.3, 95% CI: 0.18-0.45), and relapse TB (ARR = 0.6, 95% CI:0.40-0.83) were less likely to be included in RBF-model. Favorable outcomes in new/relapse cases with RBF-model was 89% compared with 41% (p < 0.001) without RBF. Similarly, for other retreatment this was 83% versus 40% (p < 0.001). Failures in the no-RBF group was 29% for new and relapse cases while for other retreatment cases, it was 26% (significantly higher than in the RBF-model).

CONCLUSION

RBF-model is effective in achieving high levels of favorable TB treatment outcomes. Almost three-in-ten TB patients in non-RBF category failed TB treatment despite having drug-susceptible TB. Efforts are now needed to include it within ongoing public health reforms and assess the feasibility of scaling-up this intervention through implementation research and dedicated funding.

摘要

引言

我们评估了基于结果的融资(RBF)模式对结核病治疗结果的影响,该模式包括对初级卫生保健机构的激励措施。

方法

2017年,我们在乌克兰敖德萨州的14个地区比较了17岁以上结核病患者及其在受益于RBF模式和未受益于该模式的患者中的治疗结果。采用对数二项回归分析与纳入RBF模式相关的因素。

结果

在报告的2269例结核病患者中,308例(14%)纳入RBF模式。RBF模式下的大多数患者来自农村地区,有229例(74%),失业者218例(71%),艾滋病毒感染者131例(43%)。来自城市地区的个体(调整风险比,ARR = 0.9,95%置信区间,CI:0.89 - 0.94)、患有耐药结核病的个体(ARR = 0.3,95% CI:0.18 - 0.45)和复发性结核病患者(ARR = 0.6,95% CI:0.40 - 0.83)被纳入RBF模式的可能性较小。RBF模式下新发病例/复发病例的良好治疗结果为89%,而无RBF模式的为41%(p < 0.001)。同样,其他复治病例的这一比例分别为83%和40%(p < 0.001)。无RBF组新发病例和复发病例的治疗失败率为29%,而其他复治病例为26%(显著高于RBF模式)。

结论

RBF模式在实现高水平的结核病良好治疗结果方面是有效的。在非RBF类别中,近十分之三的结核病患者尽管患有药敏结核病,但治疗仍告失败。现在需要努力将其纳入正在进行的公共卫生改革,并通过实施研究和专项资金评估扩大这一干预措施的可行性。

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