Alharshan Reem, Qureshi Hammad U, AlHada Abdullah, Shaikh Muhammed, Khalil Ayman
King Abdulaziz Hospital, Al Ahsaa, Saudi Arabia.
Department of Neurosurgery, King Abdulaziz Hospital, Al Ahsaa, Saudi Arabia.
Int J Surg Case Rep. 2020;67:223-226. doi: 10.1016/j.ijscr.2020.01.059. Epub 2020 Feb 6.
Diagnosing cerebral sinus venous thrombosis (CSVT) manifested as a spontaneous subdural hematoma (SDH) is challenging due to variability of its clinical features. The neuroradiological investigation is crucial to confirm the diagnosis. The management of SDH secondary to CVST is controversial and not well established.
We present a case of an adult man with Down's syndrome who underwent a left-sided craniotomy and evacuation of spontaneous subdural hematoma. Post-surgery magnetic resonance venography (MRV) revealed venous sinus thrombosis in the right transverse sinus with loss of flow signal. He was started on Apixaban two weeks post-surgery. Three months later, the patient re-presented with recurrence of the SDH. His anticoagulation was discontinued, and he underwent craniotomy reopening and evacuation of the recurrent hematoma. The patient returned to his baseline following this procedure. The patient was followed up in the out-patient clinic regularly. Interval brain MRI and MRV performed at six months showed further resolution of the thrombosis of the right sigmoid sinus with restoration of the venous flow.
The management of SDH complicating CVST remains controversial due to the rarity of its presentation and the hazards associated with the use of anticoagulation.
由于脑静脉窦血栓形成(CSVT)表现为自发性硬膜下血肿(SDH)时临床特征具有变异性,因此其诊断具有挑战性。神经放射学检查对于确诊至关重要。CVST继发SDH的治疗存在争议且尚未完全确立。
我们报告一例患有唐氏综合征的成年男性病例,该患者接受了左侧开颅手术并清除了自发性硬膜下血肿。术后磁共振静脉血管造影(MRV)显示右侧横窦静脉窦血栓形成,血流信号消失。术后两周开始使用阿哌沙班治疗。三个月后,患者再次出现SDH复发。停用抗凝药物后,他接受了开颅再次手术并清除了复发性血肿。此次手术后患者恢复至基线状态。患者在门诊定期随访。六个月时进行的间隔期脑部MRI和MRV显示右侧乙状窦血栓形成进一步消退,静脉血流恢复。
由于CVST合并SDH的病例罕见且使用抗凝药物存在风险,其治疗仍存在争议。