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Immune-mediated necrotizing myopathies and interstitial lung disease are predominant characteristics in anti-Ku positive patients with idiopathic inflammatory myopathies.

作者信息

Yang Hongxia, Li Wenli, Tian Xiaolan, Wang Guochun, Shu Xiaoming, Peng Qinglin, Lu Xin

机构信息

Department of Rheumatology, China-Japan Friendship Hospital, Beijing, China.

China-Japan Friendship School of Clinical Medicine, Peking University, Beijing, China.

出版信息

Ann Rheum Dis. 2022 Mar;81(3):e48. doi: 10.1136/annrheumdis-2020-217096. Epub 2020 Feb 17.

DOI:10.1136/annrheumdis-2020-217096
PMID:32066558
Abstract
摘要

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Immune-mediated necrotizing myopathies and interstitial lung disease are predominant characteristics in anti-Ku positive patients with idiopathic inflammatory myopathies.免疫介导的坏死性肌病和间质性肺病是抗Ku抗体阳性的特发性炎性肌病患者的主要特征。
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2
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引用本文的文献

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Anti-Ku Antibodies: Clinical Associations, Organ Damage, and Prognostic Implications in Connective Tissue Diseases.抗Ku抗体:结缔组织病中的临床关联、器官损害及预后意义
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The clinical features, muscle pathology, and role of autophagy in anti-Ku-positive patients.抗Ku阳性患者的临床特征、肌肉病理学及自噬的作用。
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Connective tissue disease-associated interstitial lung disease: a rheumatologist's perspective.
结缔组织病相关间质性肺疾病:风湿病学家的观点
Breathe (Sheff). 2025 Jun 17;21(2):240166. doi: 10.1183/20734735.0166-2024. eCollection 2025 Apr.
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J Clin Med. 2025 Jan 3;14(1):247. doi: 10.3390/jcm14010247.
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Systemic sclerosis associated myopathy: how to treat.系统性硬化症相关肌病:如何治疗。
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Pathologic Features of Anti-Ku Myositis.抗-Ku 肌炎的病理特征。
Neurology. 2024 Apr 23;102(8):e209268. doi: 10.1212/WNL.0000000000209268. Epub 2024 Mar 28.
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Interstitial lung disease associated with inflammatory myositis: Autoantibodies, clinical phenotypes, and progressive fibrosis.与炎性肌病相关的间质性肺疾病:自身抗体、临床表型和进行性纤维化。
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