Vanderbilt University Medical Center, Nashville, TN, USA.
College of Public Health, University of South Florida, Tampa, FL, USA.
Genet Med. 2020 Jun;22(6):1088-1093. doi: 10.1038/s41436-020-0762-0. Epub 2020 Feb 18.
All women diagnosed with breast cancer (BC) ≤age 50 should be referred for genetic counseling (GC) and testing. We sought to compare differences in provider practices and access across a racially and ethnically diverse population of young BC survivors.
A registry-based sample of women diagnosed with invasive BC ≤age 50 from 2009 to 2012 was recruited through the Florida Cancer Registry, and completed a questionnaire and medical record release. Differences were compared across those tested with or without the involvement of a board-certified or credentialed genetics health professional (GHP) in (1) clinical and demographic variables and (2) pretest GC elements.
Of 1622 participants, there were 440 Blacks, 285 Hispanics, and 897 Non-Hispanic Whites. Of 831 participants with medical record verification of testing provider, 170 (20%) had documentation of GHP involvement. Among the 613 who recalled a pretest discussion and had GC elements collected, those with GHP involvement were significantly more likely to recall the seven recognized GC elements.
GHP involvement was associated with adherence to nationally recommended best practices. With the expanding importance of identifying inherited cancers, it is critical to ensure equitable access to best practices across all populations.
所有被诊断患有乳腺癌（BC）且年龄≤50 岁的女性都应被推荐进行遗传咨询（GC）和检测。我们旨在比较不同种族和族裔的年轻 BC 幸存者中，提供者的实践和获得途径存在哪些差异。
通过佛罗里达州癌症登记处招募了 2009 年至 2012 年期间被诊断为侵袭性 BC 且年龄≤50 岁的女性作为基于登记的样本，并完成了问卷调查和医疗记录的释放。比较了在以下情况下参与或未参与经过董事会认证或认证的遗传健康专业人员（GHP）的参与者之间的差异：（1）临床和人口统计学变量；（2）术前 GC 元素。
在 1622 名参与者中，有 440 名黑人、285 名西班牙裔和 897 名非西班牙裔白人。在 831 名有医疗记录验证测试提供者的参与者中，有 170 名（20%）有 GHP 参与的记录。在 613 名回忆术前讨论并收集了 GC 元素的参与者中，有 GHP 参与的参与者更有可能回忆起七个公认的 GC 元素。
GHP 的参与与遵守国家推荐的最佳实践有关。随着确定遗传性癌症的重要性不断扩大，确保所有人群都能平等获得最佳实践至关重要。
