Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
College of Public Health, University of South Florida, Tampa, Florida, USA.
Genet Test Mol Biomarkers. 2023 Jan;27(1):1-4. doi: 10.1089/gtmb.2022.0160.
Scalable solutions are needed to make pre-test genetic education about inherited cancer risk accessible across diverse and underserved populations. We evaluated an automated strategy to deliver genetic education through a web-based video among young Black females with breast cancer. 96 participants were recruited through state cancer registries in Florida and Tennesee. All participants viewed a 12 min video and completed a ten question quiz on inherited cancer knowledge before and after viewing the video. Median pre- and postvideo knowledge scores were categorized as <60% versus ≥60% and compared across demographic and clinical characteristics using binary logistic regression. Of the 96 participants, mean age was 51, over 50% had income <$50 K, over 40% did not graduate college or have private insurance, and over 70% had previous genetic testing. Median knowledge scores significantly increased after viewing the video ( < 001), with no significant differences in those with or without prior testing. A higher post-video knowledge score was associated with an income ≥$50 K, a college degree, and private insurance (all < .05). Among a population of young Black breast cancer patients, the educational video significantly increased knowledge. Findings support the use of automated pre-test educational tools as a scalable solution to make these services more accessible across populations.
需要可扩展的解决方案，以便使针对遗传性癌症风险的预测试遗传教育能够覆盖到不同和服务不足的人群。我们评估了一种通过基于网络的视频向有乳腺癌的年轻黑人女性提供遗传教育的自动化策略。通过佛罗里达州和田纳西州的州癌症登记处招募了 96 名参与者。所有参与者都观看了 12 分钟的视频，并在观看视频前后完成了关于遗传性癌症知识的十个问题测验。中位数的预和视频后知识得分被分为 <60%与≥60%，并根据人口统计学和临床特征使用二项逻辑回归进行比较。在 96 名参与者中，平均年龄为 51 岁，超过 50%的人收入<$50000，超过 40%的人没有大学毕业或没有私人保险，超过 70%的人之前进行过基因测试。观看视频后，知识得分中位数显著增加（<0.001），而有或没有先前测试的人之间没有显著差异。观看视频后的更高知识得分与收入≥$50000、大学学位和私人保险相关（均<0.05）。在一群年轻的黑人乳腺癌患者中，教育视频显著增加了知识。研究结果支持使用自动化预测试教育工具作为一种可扩展的解决方案，以便在人群中更广泛地提供这些服务。
