Department of General Surgery and the Bariatric and Metabolic Institute, Cleveland Clinic Florida, 2950 Cleveland Clinic Blvd, Weston, FL, 33331, USA.
Department of General and Interventional Cardiology, Cleveland Clinic Florida, Weston, USA.
Obes Surg. 2020 May;30(5):1679-1684. doi: 10.1007/s11695-019-04341-1.
Risk factors for heart disease include arterial hypertension, high cholesterol, tobacco abuse, and obesity. There is a paucity of data regarding role of ethnicity in bariatric surgery (BS) outcomes. The study's aim is to determine if ethnicity plays a significant role in BS outcomes, heart age, and cardiovascular risk.
We conducted a retrospective review of data collected concurrently from patients who underwent BS from 2010 to 2015. We analyzed demographics, comorbidities, heart age, and cardiovascular risk-score at surgery and 12-month follow-up. Ethnicities categorized were Caucasian and African American. Heart age was calculated using the Framingham Study Heart Age Calculator and cardiovascular risk-score using the Atherosclerotic Cardiovascular Disease Risk Calculator.
A total of 292 patients presented all the variables needed to calculate heart age and cardiovascular risk score. This patient population was composed of 85% Caucasians and 15% African American. Female gender represented 67% (N = 202) of patients with mean age of 52.6 ± 10.7 years. LSG was the most prevalent procedure performed in 73.2% (N = 213) of patients. Mean BMI pre-operatively versus post-operatively by ethnicity was 41.46 ± 4.66 vs 30.08 ± 4.34 Caucasians and 41.90 ± 4.69 vs 32.08 ± 4.68 African Americans. Mean heart age pre-operatively versus post-operatively by ethnicity was 71.35 ± 14.59 vs 62.45 ± 16.12 (p < 0.0001) for Caucasians and 71.38 ± 14.30 vs 65.91 ± 16.61 (p = 0.11) for African Americans. The mean cardiovascular risk scores pre-operatively versus post-operatively by ethnicity were 0.24 ± 0.20 vs 0.15 ± 0.14 (p < 0.0001) for Caucasians and 0.20 ± 0.19 vs 0.16 ± 0.17 (p = 0.23) for African Americans.
Ethnicity does not seem to impact weight loss after BS. However, we found a significant ethnicity-elated difference in reduction of heart age and cardiovascular risk.
心脏病的风险因素包括动脉高血压、高胆固醇、滥用烟草和肥胖。关于种族在减重手术（BS）结果中的作用的数据很少。本研究旨在确定种族是否在 BS 结果、心脏年龄和心血管风险中起重要作用。
我们对 2010 年至 2015 年间接受 BS 的患者同时收集的数据进行了回顾性分析。我们分析了手术时和 12 个月随访时的人口统计学、合并症、心脏年龄和心血管风险评分。分类的种族为白种人和非裔美国人。心脏年龄使用弗雷明汉研究心脏年龄计算器计算，心血管风险评分使用动脉粥样硬化性心血管疾病风险计算器计算。
共有 292 名患者提供了计算心脏年龄和心血管风险评分所需的所有变量。该患者人群由 85%的白种人和 15%的非裔美国人组成。女性占 67%（N=202），平均年龄为 52.6±10.7 岁。LSG 是最常见的手术，在 73.2%（N=213）的患者中进行。根据种族，术前和术后的平均 BMI 分别为 41.46±4.66 vs 30.08±4.34 白种人和 41.90±4.69 vs 32.08±4.68 非裔美国人。根据种族，术前和术后的平均心脏年龄分别为 71.35±14.59 vs 62.45±16.12（p<0.0001）白种人和 71.38±14.30 vs 65.91±16.61（p=0.11）非裔美国人。根据种族，术前和术后的平均心血管风险评分分别为 0.24±0.20 vs 0.15±0.14（p<0.0001）白种人和 0.20±0.19 vs 0.16±0.17（p=0.23）非裔美国人。
种族似乎不会影响 BS 后的体重减轻。然而，我们发现心脏年龄和心血管风险的降低与种族有显著的相关性。
