Department of Internal Medicine, Ota&Jinemed Hospital, Muradiye Mahallesi Nuzhetiye Cad, Deryadil Sokagi No:1, Besiktas, 34357, Istanbul, Turkey.
Department of Biochemistry, Private Practice, Istanbul, Turkey.
Int J Cardiovasc Imaging. 2020 May;36(5):797-798. doi: 10.1007/s10554-020-01781-0. Epub 2020 Feb 18.
We read with great pleasure the interesting study evaluating "The relationship between atherogenic index of plasma (AIP) and no-reflow in patients with acute ST-segment elevation myocardial infarction who underwent primary percutaneous coronary intervention" by Süleymanoğlu M et al. The most important problem in the study was that they miscalculated their patients' AIP values. As a result of this miscalculation, all patients seemed to be at high cardiac risk. When calculating AIP, the unit of both triglyceride (TG) and high-density lipoprotein (HDL) levels should be taken in mmol. In calculating the AIP value, Süleymanoğlu et al. used the units as mg/dl and found the median values as 0.50 (patients with noreflow, high cardiac risk) and 0.39 (patients without noreflow, high cardiac risk), respectively. When we calculate the estimated AIP by converting units to mmol, it is 0.15 (patients with noreflow, intermediate cardiac risk) and 0.03 (patients with noreflow, low cardiac risk), respectively. Interestingly, their patients' cholesterol levels such as total cholesterol, TG, low-density lipoprotein, and HDL were very lower than those of healthy individuals in their country. We believe that the authors should explain this situation.
我们非常高兴地阅读了 Süleymanoğlu 等人评估“急性 ST 段抬高型心肌梗死患者行直接经皮冠状动脉介入治疗后致无复流与血浆致动脉粥样硬化指数的关系”的这项有趣的研究。该研究中最重要的问题是他们错误地计算了患者的 AIP 值。由于这种错误计算，所有患者似乎都存在高心脏风险。在计算 AIP 时，甘油三酯 (TG) 和高密度脂蛋白 (HDL) 水平的单位均应为 mmol。在计算 AIP 值时，Süleymanoğlu 等人使用 mg/dl 作为单位，并分别发现无复流（高心脏风险）患者的中位数为 0.50 和有复流（高心脏风险）患者的中位数为 0.39。当我们将单位转换为 mmol 来计算估计的 AIP 时，无复流（中等心脏风险）患者的 AIP 值分别为 0.15 和有复流（低心脏风险）患者的 AIP 值分别为 0.03。有趣的是，他们的患者的胆固醇水平（如总胆固醇、TG、低密度脂蛋白和 HDL）远低于他们国家的健康个体。我们认为作者应该解释这种情况。
