Department of Internal Medicine, Texas Tech University Health Sciences Center El Paso, 4800 Alberta Avenue, El Paso, TX, 79905, USA.
Department of Internal Medicine, Division of Cardiovascular Diseases, Texas Tech University Health Sciences Center, El Paso, TX, USA.
Curr Cardiol Rep. 2020 Feb 14;22(4):22. doi: 10.1007/s11886-020-1270-1.
The objective of this study is to explore the current literature supporting the use oral multivitamins and multi/minerals (OMVMs) for cardiovascular diseases (CVD) treatment and prevention.
Data on multivitamins, vitamin C and D, coenzyme Q, calcium, and selenium, has showed no consistent benefit for the prevention of CVD, myocardial infarction, or stroke, nor was there a benefit for all-cause mortality to support their routine supplementation. Folic acid alone and B vitamins with folic acid, B and B, reduce stroke, whereas niacin and antioxidants are associated with an increased risk of all-cause mortality. Iron deficiency should be avoided and treated if found, but routine supplementation to those without deficiency is not evidence based. Despite the high supplement use by the general public, there is no evidence to support the routine supplementation of oral multivitamins and multi/minerals (OVMN) for CVD prevention or treatment.
本研究旨在探讨目前支持使用口服多种维生素和矿物质(OMVM)治疗和预防心血管疾病(CVD)的文献。
关于多种维生素、维生素 C 和 D、辅酶 Q、钙和硒的数据表明,它们对预防 CVD、心肌梗死或中风没有一致的益处,也没有全因死亡率的益处来支持它们的常规补充。单独使用叶酸以及含叶酸、B 族维生素和 B 族维生素的 B 族维生素可降低中风风险,而烟酸和抗氧化剂则与全因死亡率增加相关。应避免缺铁和发现缺铁后进行治疗,但对无缺铁者进行常规补充则没有证据支持。尽管公众普遍大量补充,但没有证据支持常规补充口服多种维生素和矿物质(OVMN)来预防或治疗 CVD。