Department of Epidemiology, Baylor Scott and White Health, PO Box 190667, Dallas, TX 75219, USA.
Card Electrophysiol Clin. 2020 Mar;12(1):109-115. doi: 10.1016/j.ccep.2019.10.001. Epub 2019 Dec 25.
Left atrial appendage exclusion is efficacious for stroke prophylaxis in patients with atrial fibrillation. Surgical excision provides reliable left atrial appendage exclusion, whereas surgical occlusion does not. Specifically, 2-layer internal suture ligation has a high failure rate. Left atrial appendage exclusion concomitant to another cardiac surgical procedure is indicated in patients with atrial fibrillation but not in patients without baseline atrial fibrillation. Studies currently underway will further define the role of concomitant surgical left atrial appendage exclusion, especially for the population without baseline atrial fibrillation but at high risk of developing postoperative atrial fibrillation.
左心耳封堵术在预防房颤患者的中风方面是有效的。外科切除能可靠地实现左心耳封堵,而外科闭塞则不能。具体来说,双层内缝合结扎的失败率很高。对于有房颤的患者,同时进行其他心脏外科手术的左心耳封堵是有指征的,但对于没有基础房颤的患者则没有指征。目前正在进行的研究将进一步确定同时进行外科左心耳封堵的作用,特别是对于没有基础房颤但有发生术后房颤高风险的人群。