Texas Cardiac Arrhythmia Institute, St. David's Medical Center, Austin, TX, USA.
Texas Cardiac Arrhythmia Institute, St. David's Medical Center, Austin, TX, USA.
Card Electrophysiol Clin. 2020 Mar;12(1):89-96. doi: 10.1016/j.ccep.2019.11.010.
Left atrial appendage (LAA) is the dominant source of systemic thromboembolic (TE) events in patients with nonvalvular atrial fibrillation (AF). In patients with significant bleeding risk, various LAA exclusion strategies have been developed as an alternative to pharmacologic TE prophylaxis. Nevertheless, in a relatively small percentage of patients, incomplete LAA closure can be documented, either at the time of procedure or during follow-up. This persistent patency can potentially jeopardize an effective stroke prophylaxis. Hereby, we report an update on the current clinical implications of LAA leaks and how to manage them.
左心耳（LAA）是无瓣膜性心房颤动（AF）患者全身血栓栓塞（TE）事件的主要来源。对于有明显出血风险的患者，已经开发出各种 LAA 排除策略作为药物 TE 预防的替代方法。然而，在相对较小比例的患者中，无论是在手术时还是在随访期间，都可以记录到 LAA 不完全闭塞。这种持续的通畅可能会危及有效的中风预防。在此，我们报告 LAA 漏的当前临床意义的最新进展以及如何对其进行管理。
