Department of Otolaryngology-Head and Neck Surgery, 117902Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Department of Otolaryngology-Head & Neck Surgery, 1501Johns Hopkins School of Medicine, Baltimore, MA, USA.
Ear Nose Throat J. 2021 Sep;100(5_suppl):730S-733S. doi: 10.1177/0145561320904813. Epub 2020 Feb 19.
Mucosal melanoma arising in the middle ear or eustachian tube is uncommon. We present a patient with hearing loss and otalgia found to have mucosal melanoma which occurred in the eustachian tube with extension into the middle ear cavity and external ear canal. Otologic clinics was consulted and biopsy of the mass located at the external canal was performed to ascertain the pathological diagnosis. The patient refused immunotherapy and surgery instead of undergoing radiotherapy and died from hepatic metastasis 8 months later. The mucosal melanoma originated from the eustachian tube with extension into the external ear canal is exceedingly rare, and the differential diagnosis should be considered for tumors in external ear canal.
发生于中耳或咽鼓管的黏膜黑色素瘤并不常见。我们报告一位有听力丧失及耳痛的病患,经检查发现于咽鼓管有黏膜黑色素瘤,并延伸至中耳腔及外耳道。会诊耳鼻喉科后,在外耳道的肿块进行切片以确定病理诊断。病患拒绝免疫疗法及手术,选择接受放射线治疗,8 个月后因肝转移而死亡。起源于咽鼓管并延伸至外耳道的黏膜黑色素瘤极为罕见,对外耳道肿瘤应考虑此一鉴别诊断。