Department of Otolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University Faculty of Medicine, Seoul, Korea.
Department of Otolaryngology-Head and Neck Surgery, Jeju Medical Center, Jeju University Faculty of Medicine, Jeju, Korea.
J Int Adv Otol. 2022 Sep;18(5):455-458. doi: 10.5152/iao.2022.21573.
Mucosal melanoma originating from the eustachian tube is very rare, and only 15 cases were reported so far. In this study, we report a case of mucosal melanoma from the eustachian tube which was surgically managed, followed by chemoradiotherapy. A 53-year-old man presented with a history of recurrent idiopathic hemotympanum and a dark red mass in the nasopharynx protruding from the eustachian tube orifice. Under an impression of mucosal melanoma from the eustachian tube, en-bloc surgical removal was performed using the infratemporal fossa approach type C combined with a transnasal endoscopic approach followed by postoperative chemoradiotherapy. However, the disease progressed to lung metastasis, and the patient died of the disease at 13 months postoperatively. The presenting case showed a poor progression despite a margin-free surgical resection followed by chemoradiotherapy. Additional trial of new treatment options is necessary to improve the poor prognosis.
起源于咽鼓管的黏膜黑色素瘤非常罕见，迄今为止仅报告了 15 例。本研究报告了一例经手术治疗、辅以放化疗的咽鼓管黏膜黑色素瘤病例。一名 53 岁男性因复发性特发性血鼓室和鼻咽部暗红色肿块从咽鼓管口突出而就诊，该肿块被诊断为咽鼓管黏膜黑色素瘤。采用 C 型颞下窝入路联合经鼻内镜入路整块切除，术后行放化疗。然而，疾病进展为肺转移，患者术后 13 个月死于该病。尽管手术切除边缘无肿瘤且辅以放化疗，但该患者仍预后不良。需要尝试新的治疗方法来改善这种不良预后。
