Tywończuk-Szulc Monika, Kibiłda Bogdan
Oddział Laryngologii Wojewódzkiego Szpitala Specjalistycznego w Olsztynie.
Otolaryngol Pol. 2007;61(3):335-8. doi: 10.1016/S0030-6657(07)70439-0.
Melanomas of the mucous membranes of airway tract constitute around 1% of the total melanomas of head and neck. The most common site of the tumor are the nasal and paranasal sinuses but melanomas of the oral cavity are described too. The location of malignant melanoma in the eustachian tube is very rare. We found five cases of this disease in the literature. In our article we present a 53-year-old woman with progressive left aural fullness and hearing impairment for two months. Clinical examination found left middle ear effusion. The nasopharyngoscopy revealed a bluish red, friable and granulomatous tumor occupying the whole pharyngeal orifice of the left auditory tube. The biopsy speciment was taken which established the diagnosis. Because of localization and spread of the melanoma we had a low opinion of surgical treatment and radiotherapy was recommended. The patient was under constant laryngologic and oncological observation. We did not notice the local recurrence of melanoma. She died two years after making the diagnosis because of the neoplasm dissemination.
气道黏膜黑色素瘤约占头颈部黑色素瘤总数的1%。肿瘤最常见的部位是鼻腔和鼻窦，但口腔黑色素瘤也有相关报道。咽鼓管恶性黑色素瘤的位置非常罕见。我们在文献中发现了5例这种疾病。在我们的文章中，我们介绍了一名53岁的女性，她有两个月的进行性左耳闷胀和听力减退。临床检查发现左耳中耳积液。鼻咽喉镜检查发现一个蓝红色、易碎且呈肉芽肿样的肿瘤占据了左咽鼓管的整个咽口。进行了活检标本采集以明确诊断。由于黑色素瘤的位置和扩散情况，我们对手术治疗评价不高，因此建议进行放疗。该患者一直在接受耳鼻喉科和肿瘤科的持续观察。我们没有注意到黑色素瘤的局部复发。她在确诊两年后因肿瘤扩散而死亡。
