Popoff Michel R
Bacterial Toxins, Institut Pasteur, Paris, Cedex, France.
J Vet Diagn Invest. 2020 Mar;32(2):184-191. doi: 10.1177/1040638720906814. Epub 2020 Feb 18.
Tetanus is a neurologic disease of humans and animals characterized by spastic paralysis. Tetanus is caused by tetanus toxin (TeNT) produced by , an environmental soilborne, gram-positive, sporulating bacterium. The disease most often results from wound contamination by soil containing spores. Horses, sheep, and humans are highly sensitive to TeNT, whereas cattle, dogs, and cats are more resistant. The diagnosis of tetanus is mainly based on the characteristic clinical signs. Identification of at the wound site is often difficult.
破伤风是一种以痉挛性麻痹为特征的人和动物神经疾病。破伤风由破伤风杆菌产生的破伤风毒素(TeNT)引起,破伤风杆菌是一种环境中土传的革兰氏阳性产芽孢细菌。该病最常因含有破伤风杆菌芽孢的土壤污染伤口所致。马、绵羊和人类对TeNT高度敏感,而牛、狗和猫则更具抵抗力。破伤风的诊断主要基于特征性临床症状。在伤口部位鉴定破伤风杆菌往往很困难。