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无残端的有症状长节段慢性颈内动脉闭塞的杂交治疗

[Hybrid treatment for symptomatic long-segment chronic internal carotid artery occlusion without stump].

作者信息

Jia Z C, Li X, Zheng M, Luan J Y, Wang C M, Han J T

机构信息

Department of Interventional Radiology and Vascular Surgery, Peking University Third Hospital, Beijing 100191, China.

Department of Neurology, Peking University Third Hospital, Beijing 100191, China.

出版信息

Beijing Da Xue Xue Bao Yi Xue Ban. 2020 Feb 18;52(1):177-180. doi: 10.19723/j.issn.1671-167X.2020.01.028.

Abstract

OBJECTIVE

To summarize the preliminary experience of hybrid operation for the treatment of symptomatic long-segment chronic internal carotid artery occlusion (CICAO) without stump.

METHODS

Clinical data of 12 patients of symptomatic long-segment CICAO without stump undergoing hybrid operation treatment from July 2015 to December 2017 were retrospectively analyzed. The safety and efficacy of hybrid operation for the treatment of symptomatic long-segment CICAO without stump were preliminarily assessed. CICAO was defined as occlusion time being more than 4 weeks. The primary outcome was defined as any stroke (including ischemic or hemorrhagic) or deaths from any cause after hybrid operation within 30 days. The secondary outcome was defined as successful revascularization and occurrence of >50% in-stent restenosis during the follow-up period.

RESULTS

In this group, the symptomatic long-segment CICAO of 11 patients were successfully recanalized. Technical success rate was 91.7% (11/12). The main complication rate was 8.3% (1/12). This patient encountered iatrogenic internal carotid artery cavernous sinus fistula caused by micro-guide wire in the midway of the hybrid operation, the proximal segment of this internal carotid artery was ligated and the iatrogenic internal carotid artery cavernous sinus fistula disappeared in the following digital subtraction angiography image. No patient encountered hemorrhagic stroke and ischemic stroke. No death complications occurred. In this group 10 patients of them were followed up. The follow-up period ranged from 10 to 32 months [mean, (19±9) months]. During the follow-up period, 1 patients developed in-stent restenosis and improved after reoperation of percutaneous transluminal angioplasty by the right size balloon without stenting treatment.

CONCLUSION

Hybrid operation for the treatment of highly screened patients with symptomatic long-segment CICAO without stump is safe and effective, could reduce the incidence of complications and improve procedural success rate.

摘要

目的

总结杂交手术治疗无症状长节段慢性颈内动脉闭塞(CICAO)且无残端的初步经验。

方法

回顾性分析2015年7月至2017年12月期间12例无症状长节段CICAO且无残端接受杂交手术治疗患者的临床资料。初步评估杂交手术治疗无症状长节段CICAO且无残端的安全性和有效性。CICAO定义为闭塞时间超过4周。主要结局定义为杂交手术后30天内发生的任何卒中(包括缺血性或出血性)或任何原因导致的死亡。次要结局定义为随访期间成功血管再通和支架内再狭窄发生率>50%。

结果

该组中,11例无症状长节段CICAO患者成功再通。技术成功率为91.7%(11/12)。主要并发症发生率为8.3%(1/12)。该患者在杂交手术中途因微导丝导致医源性颈内动脉海绵窦瘘,该颈内动脉近端结扎,随后数字减影血管造影图像中医源性颈内动脉海绵窦瘘消失。无患者发生出血性卒中和缺血性卒中。无死亡并发症发生。该组10例患者进行了随访。随访时间为10至32个月[平均,(19±9)个月]。随访期间,1例患者发生支架内再狭窄,经右尺寸球囊经皮腔内血管成形术再次手术且未置入支架治疗后好转。

结论

杂交手术治疗经过严格筛选的无症状长节段CICAO且无残端患者安全有效,可降低并发症发生率并提高手术成功率。

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