Department of Neurology and Suzhou Clinical Research Center of Neurological Disease, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Department of Neurology, The Affiliated Wujiang Hospital of Nantong University, Suzhou, China.
Sci Prog. 2021 Jan-Mar;104(1):36850421998870. doi: 10.1177/0036850421998870.
To investigate the feasibility, efficacy, and safety of endovascular recanalization for symptomatic chronic internal carotid artery occlusions (ICAO). Thirty patients with symptomatic chronic ICAO were treated using the endovascular recanalization method. Proximal balloon protection devices were used to prevent embolic migration by completely blocking the blood flow. The morphology of the internal carotid artery (ICA) at the occluded segment based on catheter angiography was analyzed. Recanalization of symptomatic chronic internal carotid artery occlusion (CICAO) was successful in 20 of the 30 patients (66.7%). The time required for successful revascularization ranged from 120 to 180 min (mean, 150 min). Of the 20 successful patients, 14 were at the cervical ICAs, and six were at the intracranial ICAs. No permanent complications occurred in our study. Ischemic symptoms related to chronic ICAO did not occur during the 18.3 month follow-up period (range, 12-24 months) in the 20 successful patients. Endovascular revascularization can improve hemodynamic compromise. The treated sites of all 20 successfully recanalized patients were patent on computed tomographic angiography or carotid duplex sonography, and no case with >50% restenosis was observed during the follow-up period. Three patients with failed recanalization had a stroke during the follow-up period. Endovascular revascularization of symptomatic CICAO using a proximal balloon protection device is technically feasible in selected patients, and the outcomes are favorable for patients who benefit from revascularization.
为了研究血管内再通治疗症状性慢性颈内动脉闭塞(CICAO)的可行性、疗效和安全性。30 例症状性慢性颈内动脉闭塞患者采用血管内再通方法治疗。近端球囊保护装置用于通过完全阻断血流来防止栓塞迁移。根据导管血管造影分析闭塞段颈内动脉(ICA)的形态。30 例患者中,有 20 例(66.7%)成功实现了症状性慢性颈内动脉闭塞(CICAO)再通。成功再通所需的时间范围为 120 至 180 分钟(平均 150 分钟)。20 例成功患者中,14 例位于颈内动脉,6 例位于颅内颈内动脉。在 20 例成功患者的 18.3 个月随访期间(12-24 个月),没有发生与慢性颈内动脉闭塞相关的缺血症状。20 例成功再通患者的所有治疗部位在计算机断层血管造影或颈动脉双功能超声检查上均显示通畅,且在随访期间未观察到>50%的再狭窄病例。3 例再通失败的患者在随访期间发生了卒中。在选择的患者中,使用近端球囊保护装置进行症状性 CICAO 的血管内再通技术是可行的,并且对于受益于再通的患者来说,结果是有利的。