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用于治疗玩具犬种颅交叉韧带破裂的2.5毫米骨锚的体外力学性能

Ex vivo mechanical properties of a 2.5-mm bone anchor for treatment of cranial cruciate ligament rupture in toy breed dogs.

作者信息

Roca Rodrigo Y, Peura Aliisa, Kowaleski Michael P, Watson Mallory T, Lendhey Matin, Rocheleau P J, Hulse Donald A

机构信息

Boren Veterinary Teaching Hospital, Oklahoma State University, Stillwater, Oklahoma.

Espanola Animal Hospital, Espanola, Ontario, Canada.

出版信息

Vet Surg. 2020 May;49(4):736-740. doi: 10.1111/vsu.13399. Epub 2020 Feb 19.

Abstract

OBJECTIVE

To determine the mechanical pull-out properties of a 2.5-mm bone anchor implanted in ex vivo femurs of toy breed dogs and to determine whether there is a difference between knotted and knotless configurations.

STUDY DESIGN

Experimental study.

SAMPLE POPULATION

Eight paired harvested femurs.

METHODS

Femurs were assigned to knotted or knotless configuration. Equal numbers of right and left femurs were tested. The caudolateral femoral condyle at the distal pole of the lateral fabella (F2 site) was drilled. The assigned configuration with braided suture combined with the bone anchor was implanted into the F2 site. Each configuration was positioned into a mechanical testing machine to measure yield load, load at 3-mm displacement, ultimate load, stiffness, and mode of failure at the beginning of the canine standing phase angle (150°).

RESULTS

Mean ultimate load was 100.14 and 88.69 N (P = .798), mean yield load was 59.72 and 55.85 N (P = .708), load at 3-mm displacement was 46.72 and 43.33 N (P = .656), and stiffness was calculated to be 43.06 and 47.09 N/mm (P = .548) for knotted and knotless configurations, respectively. Mode of failure occurred primarily by anchor pull-out.

CONCLUSION

The bone anchor withstood deformation at the estimated forces applied on the native cranial cruciate ligament (CCL) of toy breed dogs in both configurations.

CLINICAL SIGNIFICANCE

This bone anchor may constitute a useful alternative for stabilization of the CCL deficient stifle in toy breed dogs. However, before it can be recommended for widespread use in dogs, closely monitored clinical trials must be conducted to assess outcome and complications associated with this implant.

摘要

目的

测定植入玩具犬离体股骨的2.5毫米骨锚的机械拔出性能,并确定打结和无结构型之间是否存在差异。

研究设计

实验研究。

样本群体

八对采集的股骨。

方法

将股骨分为打结或无结构型。对左右股骨进行等量测试。在外侧腓肠豆远端极的后外侧股骨髁(F2位点)钻孔。将指定构型的编织缝线与骨锚结合植入F2位点。每种构型置于机械试验机中,以测量犬站立相起始角度(150°)时的屈服载荷、3毫米位移时的载荷、极限载荷、刚度和失效模式。

结果

打结和无结构型的平均极限载荷分别为100.14和88.69 N(P = 0.798),平均屈服载荷分别为59.72和55.85 N(P = 0.708),3毫米位移时的载荷分别为46.72和43.33 N(P = 0.656),刚度分别计算为43.06和47.09 N/mm(P = 0.548)。失效模式主要为锚钉拔出。

结论

在两种构型中,骨锚在施加于玩具犬天然颅交叉韧带(CCL)的估计力作用下均能承受变形。

临床意义

这种骨锚可能是稳定玩具犬CCL缺陷 stifle的一种有用替代方法。然而,在推荐其广泛应用于犬类之前,必须进行密切监测的临床试验,以评估与该植入物相关的结果和并发症。

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