Biskup Jeffery J, Balogh Daniel G, Haynes Kevin H, Freeman Andy L, Conzemius Michael G
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN 37996.
Am J Vet Res. 2015 May;76(5):411-9. doi: 10.2460/ajvr.76.5.411.
To test ex vivo mechanical properties of 4 allograft fixation techniques for cranial cruciate ligament (CCL) replacement.
30 stifle joints from canine cadavers.
CCL-deficient stifle joints repaired by 1 of 4 techniques (n = 6/group) and CCL-intact stifle joints (control group; 6) were mechanically tested. Three repair techniques involved a patella-patella ligament segment (PPL) allograft: a tibial and femoral interference screw (PPL-2S), a femoral interference screw and the patella seated in a tapering bone tunnel in the tibia (PPL-1S), or addition of a suture and a bone anchor to the PPL-1S (PPL-SL). The fourth technique involved a deep digital flexor tendon (DDFT) allograft secured with transverse femoral fixation and stabilized with a tibial interference screw and 2 spiked washers on the tibia (DDFT-TF). The tibia was axially loaded at a joint angle of 135°. Loads to induce 3, 5, and 10 mm of femoral-tibia translation; stiffness; and load at ultimate failure with the corresponding displacement were calculated. Group means were compared with a multivariate ANOVA.
Mean ± SD load for the intact (control) CCL was 520.0 ± 51.3 N and did not differ significantly from the load needed to induce 3 mm of femoral-tibial translation for fixation techniques PPL-SL (422.4 ± 46.3 N) and DDFT-TF (654.2 ± 117.7 N). Results for the DDFT-TF were similar to those of the intact CCL for all outcome measures.
The DDFT-TF yielded mechanical properties similar to those of intact CCLs and may be a viable technique to test in vivo.
测试用于颅交叉韧带（CCL）置换的4种同种异体移植固定技术的体外力学性能。
来自犬类尸体的30个 stifle关节。
采用4种技术之一修复CCL缺陷的stifle关节（每组n = 6），并对CCL完整的stifle关节（对照组；6个）进行力学测试。三种修复技术涉及髌腱-髌韧带节段（PPL）同种异体移植：胫骨和股骨干涉螺钉（PPL-2S）、股骨干涉螺钉以及髌骨置于胫骨逐渐变细的骨隧道中（PPL-1S），或在PPL-1S基础上加用缝线和骨锚（PPL-SL）。第四种技术涉及用股骨横向固定固定的深部指屈肌腱（DDFT）同种异体移植，并在胫骨上用胫骨干涉螺钉和2个带尖垫圈进行稳定（DDFT-TF）。在135°关节角度下对胫骨进行轴向加载。计算导致股骨-胫骨平移3、5和10 mm的载荷、刚度以及最终失效时的载荷及相应位移。采用多因素方差分析比较组均值。
完整（对照）CCL的平均±标准差载荷为520.0±51.3 N，与PPL-SL（422.4±46.3 N）和DDFT-TF（654.2±117.7 N）固定技术导致股骨-胫骨平移3 mm所需的载荷无显著差异。对于所有结果指标，DDFT-TF的结果与完整CCL的结果相似。
DDFT-TF产生的力学性能与完整CCL相似，可能是一种可行的体内测试技术。
