Nikeghbalian Saman, Arasteh Peyman, Nikoupour Hamed
Shiraz Transplant Center, Abu-Ali Sina Hospital.
Shiraz Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Curr Opin Organ Transplant. 2020 Apr;25(2):169-175. doi: 10.1097/MOT.0000000000000751.
Intestinal transplantations are among the most complex transplantations, which are performed in few centers in the world. When patients develop intestinal failure, different treatment modalities including parenteral nutrition, autologous gastrointestinal tract reconstructive surgery, and intestinal transplantations are considered. The Middle East is a region where reports on intestinal failures and intestinal transplantations are mainly lacking. In the present review, we highlighted the status of intestinal transplantations in the Middle East and focused on existing reports from this region.
Very few countries in the Middle East have the facilities for home parenteral nutrition and only two countries including Iran and Turkey perform intestinal transplantations in the region. With advances in intestinal rehabilitation units and development of autologous gastrointestinal tract reconstructive surgery, some centers have been able to reduce the number of patients in need of intestinal transplantations.
An overview of the condition of intestinal transplantations in the Middle East shows that the issue of intestinal failure and the treatment facilities still remain an unsolved problem. Although there exists a high need for intestinal transplantation, advances in reconstructive surgeries and the development of parenteral nutrition in this region can significantly reduce the need for intestinal transplantations among patients with intestinal failure.
肠道移植是最复杂的移植手术之一,全球仅有少数几个中心开展此类手术。当患者出现肠衰竭时,会考虑包括肠外营养、自体胃肠道重建手术和肠道移植在内的不同治疗方式。中东地区主要缺乏关于肠衰竭和肠道移植的报道。在本综述中,我们重点介绍了中东地区肠道移植的现状,并着重关注该地区现有的报道。
中东地区只有极少数国家具备家庭肠外营养的条件,该地区仅有伊朗和土耳其两个国家开展肠道移植手术。随着肠道康复单元的发展以及自体胃肠道重建手术的进步,一些中心已能够减少需要进行肠道移植的患者数量。
中东地区肠道移植状况的概述表明,肠衰竭问题和治疗设施仍然是一个未解决的问题。尽管对肠道移植的需求很高,但该地区重建手术的进展和肠外营养的发展可显著降低肠衰竭患者对肠道移植的需求。