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混合性结缔组织病中的关节内磷灰石沉积：晶体学和锝扫描特征

Intra-articular apatite deposition in mixed connective tissue disease: crystallographic and technetium scanning characteristics.

作者信息

Hutton C W, Maddison P J, Collins A J, Berriman J A

机构信息

Royal National Hospital for Rheumatic Diseases, Bath.

出版信息

Ann Rheum Dis. 1988 Dec;47(12):1027-30. doi: 10.1136/ard.47.12.1027.

DOI:10.1136/ard.47.12.1027
PMID:3207385
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1003660/
Abstract

An acute arthritis in a patient with mixed connective tissue disease (MCTD) was found to be associated with intra-articular deposition of carbonated hydroxyapatite crystals. A technetium hydroxymethylene diphosphonate bone scan showed intense uptake in the delayed phase scan of the affected joints. Synovial fluid analysis demonstrated uptake of the radiopharmaceutical drug directly onto the crystals.

摘要

一名混合性结缔组织病（MCTD）患者的急性关节炎被发现与关节内碳酸羟基磷灰石晶体沉积有关。锝亚甲基二膦酸盐骨扫描显示，在受累关节的延迟期扫描中有强烈摄取。滑液分析表明放射性药物直接摄取到晶体上。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b8/1003660/04d75fa9dd60/annrheumd00422-0061-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b8/1003660/1e113d0b46a8/annrheumd00422-0060-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b8/1003660/a85b31de60a6/annrheumd00422-0060-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b8/1003660/04d75fa9dd60/annrheumd00422-0061-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b8/1003660/1e113d0b46a8/annrheumd00422-0060-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b8/1003660/a85b31de60a6/annrheumd00422-0060-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b8/1003660/04d75fa9dd60/annrheumd00422-0061-a.jpg

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本文引用的文献

1
Calcifying tendinitis of the shoulder: prognostic value of clinical, histologic, and radiologic features in 57 surgically treated cases.
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Arthritis Rheum. 1972 Mar-Apr;15(2):157-73. doi: 10.1002/art.1780150205.
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Mixed connective tissue disease--an apparently distinct rheumatic disease syndrome associated with a specific antibody to an extractable nuclear antigen (ENA).混合性结缔组织病——一种明显独特的风湿性疾病综合征，与针对可提取核抗原（ENA）的特异性抗体相关。
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Systemic lupus erythematosus and gout.系统性红斑狼疮与痛风。
Semin Arthritis Rheum. 1985 Feb;14(3):176-9. doi: 10.1016/0049-0172(85)90036-8.
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Synovial calcification in a patient with collagen-vascular disease: light and electron microscopic studies.胶原血管病患者的滑膜钙化：光镜和电镜研究
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Intra-articular calcification in scleroderma.硬皮病中的关节内钙化
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Articular manifestations of mixed connective tissue disease.
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The arthritis of mixed connective tissue disease.混合性结缔组织病的关节炎
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