锝-99m 亚甲基二膦酸盐（HMDP）：一种用于骨骼和急性心肌梗死显像的放射性药物。II. 在犬模型中锝-99m 亚甲基二膦酸盐（HMDP）与其他锝标记骨显像剂的比较。
Tc-99m HMDP (hydroxymethylene diphosphonate): a radiopharmaceutical for skeletal and acute myocardial infarct imaging. II. Comparison of Tc-99m hydroxymethylene diphosphonate (HMDP) with other technetium-labeled bone-imaging agents in a canine model.
作者信息
Bevan J A, Tofe A J, Benedict J J, Francis M D, Barnett B L
出版信息
J Nucl Med. 1980 Oct;21(10):967-70.
PMID:6252299
Abstract
Technetium-99m hydroxymethylene diphosphate (Tc-HMDP) was compared with the two other diphosphonates (Tc-MDP and Tc-HEDP) and Tc-99m pyrophosphate (Tc-PPi) in a canine model of acute myocardial infarction. The TC-HMDP showed higher uptake in infarcted myocardium than the other two diphosphonates, and uptake equivalent to that of Tc-PPi.
摘要
在犬急性心肌梗死模型中，对锝-99m亚甲基二膦酸盐（Tc-HMDP）与其他两种二膦酸盐（Tc-MDP和Tc-HEDP）以及锝-99m焦磷酸盐（Tc-PPi）进行了比较。结果显示，与其他两种二膦酸盐相比，Tc-HMDP在梗死心肌中的摄取量更高，且摄取量与Tc-PPi相当。
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