Krieger J N, Tapia L, Stubenbord W T, Stenzel K H, Rubin A L
Urology. 1977 Feb;9(2):130-6. doi: 10.1016/0090-4295(77)90181-9.
Urinary tract infection is the most frequent complication following renal transplantation and is important in the etiology of post-transplantation sepsis. The 87 renal homografts done in 1974 at The New York Hospital-Cornell Medical Center were reviewed retrospectively, with at least one year follow-up, in all cases, with particular attention to factors relating urinary tract infection to ultimate success or failure of the renal graft. The over-all incidence of urinary tract infection was 61%. Early infection was associated with a particularly poor prognosis for graft survival. Most patients with urinary infections after successful transplantation experience a combination of both early and late infections. Anatomic factors constitute a remediable cause of urinary infections after transplantation and should be searched for in cases of multiple, recurrent infections, de novo hypertension, or deterioration of previously stable graft function. There were significant differences in the bacteriologic spectrum of urinary tract infections associated with successful transplants as opposed to unsuccessful transplants.
尿路感染是肾移植后最常见的并发症，在移植后败血症的病因中很重要。对1974年在纽约医院-康奈尔医学中心进行的87例肾同种异体移植进行了回顾性研究，所有病例均进行了至少一年的随访，特别关注与尿路感染导致肾移植最终成功或失败相关的因素。尿路感染的总体发生率为61%。早期感染与移植物存活的预后特别差有关。大多数成功移植后发生尿路感染的患者同时经历了早期和晚期感染。解剖学因素是移植后尿路感染的一个可补救原因，在多次复发感染、新发高血压或先前稳定的移植物功能恶化的病例中应进行检查。成功移植与未成功移植相关的尿路感染细菌谱存在显著差异。
