Thoracic Surgery, Okayama University Hospital, Okayama, Japan.
Organ Transplant Center, Okayama University Hospital, Okayama, Japan.
BMC Pulm Med. 2020 Feb 19;20(1):46. doi: 10.1186/s12890-020-1075-4.
Lung transplantation (LTx) is still limited by the shortage of suitable donor lungs. Developing flexible surgical procedures can help to increase the chances of LTx by unfolding recipient-to-donor matching options based on the pre-existing organ allocation concept. We report a case in which a successful left-to-right inverted LTx was completed using the interposition of a pericardial conduit for pulmonary venous anastomosis.
A left lung graft was offered to a 59-year-old male who had idiopathic pulmonary fibrosis with predominant damage in the right lung. He had been prescribed bed rest with constant oxygen inhalation through an oxymizer pendant and had been on the waiting list for 20 months. Considering the condition of the patient (LAS 34.3) and the scarcity of domestic organ offers, the patient was highly likely to be incapable of tolerating any additional waiting time for another donor organ if he was unable to accept the presently reported offer of a left lung. Eventually, we decided to transplant the left donor lung into the right thorax of the recipient. Because of the anterior-posterior position gap of the hilar structures, the cuff lengths of the pulmonary veins had to be adjusted. The patient did not develop any anastomotic complications after the transplantation.
A left-to-right inverted LTx is technically feasible using an autologous pericardial conduit for pulmonary venous anastomosis in selected cases. This technique provides the potential benefit of resolving challenging situations in which surgeons must deal with a patient's urgency and the logistical limitations of organ allocation.
肺移植(LTx)仍然受到合适供体肺短缺的限制。开发灵活的手术程序可以帮助增加 LTx 的机会,方法是根据预先存在的器官分配概念展开受体与供体匹配的选择。我们报告了一例成功使用心包导管进行肺静脉吻合的左右倒置 LTx。
一名 59 岁男性患有特发性肺纤维化,右肺损伤为主,我们为其提供了一个左肺移植物。该患者一直遵医嘱卧床休息,通过氧气增湿器挂件持续吸氧,并且已经在等待名单上等待了 20 个月。考虑到患者的情况(LAS 34.3)和国内器官供应的稀缺性,如果患者无法接受目前提供的左肺,他很可能无法再承受任何额外的等待时间来等待另一个供体器官。最终,我们决定将左供肺移植到受者的右胸腔。由于肺门结构的前后位置间隙,肺静脉袖口的长度需要进行调整。移植后患者没有出现任何吻合并发症。
在选择的病例中,使用自体心包导管进行肺静脉吻合的左右倒置 LTx 在技术上是可行的。该技术为解决外科医生必须应对患者的紧迫性和器官分配的后勤限制的具有挑战性的情况提供了潜在的益处。